KEGG   DRUG: D00847Help
Entry
D00847                      Drug                                   

Name
Oxycodone hydrochloride (USP);
Oxecta (TN);
Oxycontin (TN);
Roxicodone (TN)
Product
OXYCODONE HCL CONTROLLED-RELEASE (Ranbaxy Pharmaceuticals), OXYCONTIN (Blenheim Pharmacal), OXYCONTIN (Bryant Ranch Prepack), OXYCONTIN (Bryant Ranch Prepack), OXYCONTIN (Lake Erie Medical DBA Quality Care Products LLC), OXYCONTIN (Lake Erie Medical DBA Quality Care Products LLC), OXYCONTIN (Lake Erie Medical DBA Quality Care Products LLC), OXYCONTIN (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lehigh Valley Technologies), OXYCODONE HYDROCHLORIDE (Lehigh Valley Technologies), ROXICODONE (Mallinckrodt), OXYCONTIN (PD-Rx Pharmaceuticals), OXYCONTIN (PD-Rx Pharmaceuticals), OXYCONTIN (PD-Rx Pharmaceuticals), OXYCONTIN (PD-Rx Pharmaceuticals), OXECTA (Pfizer Laboratories Div Pfizer), OXYCONTIN (Purdue Pharma LP), OXYCONTIN (Rebel Distributors Corp), OXYCONTIN (Rebel Distributors Corp), OXYCONTIN (Rebel Distributors Corp), OXYCONTIN (STAT RX USA LLC), ROXICODONE (STAT RX USA LLC), OXYCONTIN (STAT Rx USA LLC), OXYCONTIN (STAT Rx USA LLC), OXYCONTIN (St Marys Medical Park Pharmacy), OXYCODONE HYDROCHLORIDE (VistaPharm), ROXICODONE (Xanodyne Pharmaceuticals)
  Generic
OXYCODONE HYDCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), OXYCODONE HYDCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Actavis Elizabeth LLC), OXYCODONE HYDROCHLORIDE (Alvogen), OXYCODONE HYDROCHLORIDE (Alvogen), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (American Health Packaging), OXYCODONE HYDCHLORIDE (American Health Packaging), OXYCODONE HYDROCHLORIDE (Aurolife Pharma LLC), OXYCODONE HYDROCHLORIDE (Blenheim Pharmacal), OXYCODONE HYDROCHLORIDE (Blenheim Pharmacal), OXYCODONE HYDROCHLORIDE (Blenheim Pharmacal), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYCODONE HYDROCHLORIDE (Caraco Pharmaceutical Laboratories), OXYCODONE HYDROCHLORIDE (CorePharma), OXYCODONE HYDROCHLORIDE (Dispensing Solutions), OXYCODONE HYDROCHLORIDE (Ethex Corporation), OXYCODONE HYDROCHLORIDE (Glenmark Generics), OXYCODONE HYDROCHLORIDE (Glenmark Generics), OXYCODONE HYDROCHLORIDE (H.J. Harkins Company), OXYCODONE HYDROCHLORIDE (H.J. Harkins Company), OXYCODONE HYDROCHLORIDE (KVK-TECH), OXYCODONE HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYCODONE HYDROCHLORIDE (Mallinckrodt), OXYCODONE HYDROCHLORIDE (Midlothian Laboratories), OXYCODONE HYDROCHLORIDE (Midlothian Laboratories), OXYCODONE HYDROCHLORIDE (Mylan Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (PD-Rx Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Physicians Total Care), OXYCODONE HYDROCHLORIDE (Physicians Total Care), OXYCODONE HYDROCHLORIDE (Qualitest Pharmaceuticals), OXYCODONE HYDROCHLORIDE (Rebel Distributors Corp), OXYCODONE HYDROCHLORIDE (Rhodes Pharmaceuticals L.P.), OXYCODONE HYDROCHLORIDE (Roxane Laboratories), OXYCODONE HYDROCHLORIDE (Roxane Laboratories), OXYCODONE HYDROCHLORIDE (STAT RX LLC USA), OXYCODONE HYDROCHLORIDE (STAT RX USA LLC), OXYCODONE HYDROCHLORIDE (STAT Rx USA LLC), OXYCODONE HYDROCHLORIDE (Safecor Health), OXYCODONE HYDROCHLORIDE (St Marys Medical Park Pharmacy), OXYCODONE HYDROCHLORIDE (St Marys Medical Park Pharmacy), OXYCODONE HYDROCHLORIDE (VistaPharm), OXYCODONE HYDROCHLORIDE (Zydus Pharmaceuticals (USA)), OXYCODONE HYDROCHLORIDE (bryant ranch prepack), OXYCODONE HYDROCHLORIDE (bryant ranch prepack)
  Other
Formula
C18H21NO4. HCl
Exact mass
351.1237
Mol weight
351.8246
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Analgesic [narcotic]
Remark
Same as: 
ATC code: 
Target
mu-opioid receptor agonist [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576], CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Opioid analgesics
Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA05 Oxycodone
      D00847  Oxycodone hydrochloride (USP)
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Oxycodone
    D00847  Oxycodone hydrochloride (USP)
  Opioid Analgesics, Short-acting
   Oxycodone
    D00847  Oxycodone hydrochloride (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    mu-opioid receptor [HSA:4988] [KO:K04215]
     Oxycodone [ATC:N02AA05]
      D00847  Oxycodone hydrochloride (USP)
BRITE hierarchy
Other DBs
CAS: 
124-90-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1z C    24.4381  -17.6672
            2   C8y C    24.4321  -16.3168
            3   C1z C    25.6030  -18.3338
            4   C1y C    23.2847  -18.3454
            5   C8y C    23.2672  -15.6445
            6   C8y C    25.5972  -15.6445
            7   C1y C    26.7623  -17.6499
            8   C1x C    25.6087  -19.6668
            9   O1a O    26.7623  -19.2729
            10  O2x O    22.5833  -17.0126
            11  C5x C    23.2905  -19.6784
            12  C8y C    23.2672  -14.2999
            13  C1x C    26.7623  -16.3109
            14  C8x C    25.5972  -14.2999
            15  N1y N    27.9213  -18.3221
            16  C1x C    24.4554  -20.3450
            17  O5x O    22.1139  -20.3391
            18  C8x C    24.4321  -13.6277
            19  O2a O    22.0966  -13.6277
            20  C1a C    29.2659  -18.3221
            21  C1x C    27.9213  -16.9998
            22  C1x C    25.6435  -17.0412
            23  C1a C    20.8657  -14.3423
            24  X   Cl   29.6100  -14.9100
BOND        27
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     3   8 1
            8     3   9 1 #Up
            9     4  10 1 #Down
            10    4  11 1
            11    5  12 2
            12    6  13 1
            13    6  14 1
            14    7  15 1 #Up
            15    8  16 1
            16   11  17 2
            17   12  18 1
            18   12  19 1
            19   15  20 1
            20    5  10 1
            21    7  13 1
            22   11  16 1
            23   14  18 2
            24   15  21 1
            25    1  22 1 #Up
            26   22  21 1
            27   19  23 1

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