 | | DRUG: Chlorhexidine gluconate | |
| Entry |
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| Name |
Chlorhexidine gluconate (JP18/USP);
Hibiclens (TN);
Peridex (TN);
Periogard (TN) |
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| Product |
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| Generic |
ACCLEAN CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Henry Schein), ACCLEAN CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Henry Schein), ACCLEAN CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Henry Schein), ACCLEAN CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Henry Schein), ACCLEAN CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Xttrium Laboratories), ACCLEAN CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE (A-S Medication Solutions), CHLORHEXIDINE GLUCONATE (ATLANTIC BIOLOGICALS CORP.), CHLORHEXIDINE GLUCONATE (American Health Packaging), CHLORHEXIDINE GLUCONATE (Benco Dental), CHLORHEXIDINE GLUCONATE (Darby Dental Supply), CHLORHEXIDINE GLUCONATE (Den-mat Holdings), CHLORHEXIDINE GLUCONATE (Lyne Laboratories), CHLORHEXIDINE GLUCONATE (Medline Industries), CHLORHEXIDINE GLUCONATE (Pharmaceutical Associates), CHLORHEXIDINE GLUCONATE (Preferred Pharmaceuticals), CHLORHEXIDINE GLUCONATE (Preferred Pharmaceuticals), CHLORHEXIDINE GLUCONATE (Proficient Rx LP), CHLORHEXIDINE GLUCONATE (Proficient Rx LP), CHLORHEXIDINE GLUCONATE (RPK Pharmaceuticals), CHLORHEXIDINE GLUCONATE (RedPharm Drug), CHLORHEXIDINE GLUCONATE (VistaPharm), CHLORHEXIDINE GLUCONATE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Chartwell RX), CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Xttrium Laboratories), CHLORHEXIDINE GLUCONATE ORAL RINSE (Rising Pharma Holdings), CHLORHEXIDINE GLUCONATE, 0.12% ORAL RINSE (American Health Packaging), CHLORHEXIDINE GLUCONATE, 0.12% ORAL RINSE SOLUTION (Bajaj Medical), CHLORHEXIDINE GLUCONATE, 0.12% ORAL RINSE SOLUTION (Kesin Pharma Corporation), CLEANCARE CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Safco Dental Supply LLC), CLEANCARE CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Safco Dental Supply LLC), DASH CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Cardinal Health 107), DASH CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Cardinal Health 107), DASH CHLORHEXIDINE GLUCONATE 0.12% ORAL RINSE (Natco Pharma USA LLC), DENTI-CARE DENTI-RINSE (Xttrium Laboratories), MAJOR ORAL RINSE (Cardinal Health 107), MAJOR ORAL RINSE (Cardinal Health 107), MAJOR ORAL RINSE (Major Pharmaceuticals), NUPRO CHLORHEXIDINE GLUCONATE (Dentsply LLC. Professional Division Trading as "DENTSPLY Professional"), NUPRO CHLORHEXIDINE GLUCONATE (Xttrium Laboratories), PERIOGARD ALCOHOL FREE (Colgate Oral Pharmaceuticals), PERIOGARD ALCOHOL FREE (Colgate Oral Pharmaceuticals), SKY ORAL RINSE (McKesson) |
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| Formula |
C22H30Cl2N10. (C6H12O7)2
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| Exact mass |
896.3198
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| Mol weight |
897.7572
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| Structure |
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| Simcomp |
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| Remark |
| Therapeutic category: | 2619 |
| Product (DG00001): | D00858<JP/US> |
| Product (mixture): | D10301<JP> |
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| Efficacy |
Antibacterial, Disinfectant, Cell membrane function inhibitor |
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| Comment |
Biguanide
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| Target |
Lipopolysaccharide
Lipoteichoic acid |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB03 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
B BLOOD AND BLOOD FORMING ORGANS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05C IRRIGATING SOLUTIONS
B05CA Antiinfectives
B05CA02 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
D DERMATOLOGICALS
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
D08AC Biguanides and amidines
D08AC02 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
D09 MEDICATED DRESSINGS
D09A MEDICATED DRESSINGS
D09AA Medicated dressings with antiinfectives
D09AA12 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
R RESPIRATORY SYSTEM
R02 THROAT PREPARATIONS
R02A THROAT PREPARATIONS
R02AA Antiseptics
R02AA05 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AX Other antiinfectives
S01AX09 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA09 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA04 Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Dental and Oral Agents
Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
261 Antimicrobial agents
2619 Others
D00858 Chlorhexidine gluconate (JP18/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for respiratory organs
27 Gargles
D00858 Chlorhexidine gluconate (JP18/USP)
Agents for integumentary system
54 Disinfectants (incl. special bandages)
D00858 Chlorhexidine gluconate (JP18/USP)
56 Purulent skin remedies
D00858 Chlorhexidine gluconate (JP18/USP)
Agents for sanitation
81 Disinfectants
D00858 Chlorhexidine gluconate (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Chlorhexidine
D00858 Chlorhexidine gluconate (JP18/USP)
Animal drugs in Japan [BR:br08331]
99 Agents for not mainly purpose of therapeutic
992 Amphoteric soap and preparations
9929 Other agents for disinfections
D00858 Chlorhexidine gluconate
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00858 Chlorhexidine gluconate solution
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| Other DBs |
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| KCF data |
ATOM 60
1 C8y C 16.8209 -12.4495
2 N1b N 18.0443 -13.1396
3 C8x C 15.6133 -13.1396
4 C8x C 16.8209 -11.0381
5 C2c C 19.2438 -12.4338
6 C8x C 14.4059 -12.4495
7 C8x C 15.6133 -10.3323
8 N1b N 20.4592 -13.1396
9 N2a N 19.2438 -11.0381
10 C8y C 14.4059 -11.0381
11 C2c C 21.6746 -12.4338
12 X Cl 13.1825 -10.3323
13 N1b N 22.8901 -13.1396
14 N2a N 21.6746 -11.0381
15 C1b C 24.1055 -12.4338
16 C1b C 25.3287 -13.1396
17 C1b C 26.5361 -12.4338
18 C1b C 27.7516 -13.1396
19 C1b C 28.9670 -12.4338
20 C1b C 30.1744 -13.1317
21 N1b N 31.3978 -12.4338
22 C2c C 32.6053 -13.1317
23 N1b N 33.8285 -12.4338
24 N2a N 32.6053 -14.5354
25 C2c C 35.0362 -13.1317
26 N1b N 36.2594 -12.4338
27 N2a N 35.0362 -14.5354
28 C8y C 37.4669 -13.1317
29 C8x C 37.4591 -14.5274
30 C8x C 38.6666 -12.4261
31 C8x C 38.6666 -15.2176
32 C8x C 39.8820 -13.1160
33 C8y C 39.8820 -14.5117
34 X Cl 41.0975 -15.2176
35 C1c C 25.2700 -16.9400
36 C1c C 26.4600 -17.6400
37 C1c C 24.0800 -17.6400
38 O1a O 25.2700 -15.5400
39 C1c C 27.7200 -16.9400
40 O1a O 26.4600 -19.0400
41 C1b C 22.8900 -16.9400
42 O1a O 24.0800 -19.0400
43 C6a C 28.9100 -17.6400
44 O1a O 27.7200 -15.5400
45 O1a O 21.6300 -17.6400
46 O6a O 30.1000 -16.9400
47 O6a O 28.9100 -19.0400
48 C1c C 25.2700 -16.9400
49 C1c C 26.4600 -17.6400
50 C1c C 27.7200 -16.9400
51 C6a C 28.9100 -17.6400
52 O6a O 30.1000 -16.9400
53 O6a O 28.9100 -19.0400
54 O1a O 27.7200 -15.5400
55 O1a O 26.4600 -19.0400
56 C1c C 24.0800 -17.6400
57 C1b C 22.8900 -16.9400
58 O1a O 21.6300 -17.6400
59 O1a O 24.0800 -19.0400
60 O1a O 25.2700 -15.5400
BOND 59
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 2
9 6 10 2
10 8 11 1
11 10 12 1
12 11 13 1
13 11 14 2
14 13 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 21 22 1
22 22 23 1
23 22 24 2
24 23 25 1
25 25 26 1
26 25 27 2
27 26 28 1
28 28 29 2
29 28 30 1
30 29 31 1
31 30 32 2
32 31 33 2
33 33 34 1
34 7 10 1
35 32 33 1
36 35 36 1
37 35 37 1
38 35 38 1 #Up
39 36 39 1
40 36 40 1 #Up
41 37 41 1
42 37 42 1 #Down
43 39 43 1
44 39 44 1 #Up
45 41 45 1
46 43 46 1
47 43 47 2
48 48 49 1
49 48 56 1
50 48 60 1 #Up
51 49 50 1
52 49 55 1 #Up
53 56 57 1
54 56 59 1 #Down
55 50 51 1
56 50 54 1 #Up
57 57 58 1
58 51 52 1
59 51 53 2
BRACKET 1 20.3000 -19.7400 20.3000 -14.8400
1 31.2200 -14.8400 31.2200 -19.7400
1 2
ORIGINAL 1 35 36 39 43 46 47 44 40 37 41 45 42 38
REPEAT 1 48 49 50 51 52 53 54 55 56 57 58 59 60
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