KEGG   DRUG: D00869Help
Entry
D00869                      Drug                                   

Name
Spectinomycin hydrochloride hydrate (JP16);
Spectinomycin hydrochloride (USP);
Trobicin (TN)
Formula
C14H24N2O7. 2HCl. 5H2O
Exact mass
494.1645
Mol weight
495.3478
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial [DS:H00315]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX04 Spectinomycin
      D00869  Spectinomycin hydrochloride hydrate (JP16); Spectinomycin hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   612  Acting mainly on gram-negative bacteria
    6124  Spectinomycins
     D00869  Spectinomycin hydrochloride hydrate (JP16); Spectinomycin hydrochloride (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Aminoglycosides
     Spectinomycin
      D00869  Spectinomycin hydrochloride hydrate (JP16); Spectinomycin hydrochloride (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00869  Spectinomycin hydrochloride hydrate
BRITE hierarchy
Other DBs
CAS: 
22189-32-8
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        30
            1   C1y C     8.8211  -14.0729
            2   C1y C     8.8211  -12.6739
            3   C1y C     7.6065  -14.7787
            4   O2x O    10.0421  -14.7724
            5   O2x O    10.0358  -11.9616
            6   C1y C     7.6065  -11.9807
            7   C1y C     6.4109  -14.0729
            8   N1b N     7.6065  -16.1651
            9   C1z C    11.3394  -14.1491
            10  C1y C    11.3267  -12.6675
            11  C1y C     6.4109  -12.6739
            12  O1a O     7.6065  -10.7406
            13  O1a O     5.2091  -14.7597
            14  C1a C     6.4047  -16.8519
            15  C5x C    12.5732  -14.7787
            16  O1a O    11.3331  -15.7328
            17  O2x O    12.6177  -11.9363
            18  N1b N     5.2156  -11.9807
            19  C1x C    13.8069  -14.1364
            20  O5x O    12.5859  -16.0951
            21  C1y C    13.7877  -12.6357
            22  C1a C     4.0135  -12.6739
            23  C1a C    14.9770  -11.9363
            24  X   Cl   19.3200  -12.1800
            25  O0  O    19.8100  -15.1900
            26  X   Cl   19.3200  -12.1800
            27  O0  O    19.8100  -15.1900
            28  O0  O    19.8100  -15.1900
            29  O0  O    19.8100  -15.1900
            30  O0  O    19.8100  -15.1900
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1 #Up
            5     2   6 1
            6     3   7 1
            7     3   8 1 #Up
            8     4   9 1
            9     5  10 1
            10    6  11 1
            11    6  12 1 #Down
            12    7  13 1 #Up
            13    8  14 1
            14    9  15 1
            15    9  16 1 #Up
            16   10  17 1
            17   11  18 1 #Up
            18   15  19 1
            19   15  20 2
            20   17  21 1
            21   18  22 1
            22   21  23 1 #Down
            23    7  11 1
            24    9  10 1
            25   19  21 1
BRACKET     1    17.5700  -13.1600   17.5700  -11.2700
            1    20.5100  -11.2700   20.5100  -13.1600
            1  2
 ORIGINAL  1   25
 REPEAT    1   27
            2    17.3600  -15.9600   17.3600  -14.3500
            2    20.8600  -14.3500   20.8600  -15.9600
            2  5
 ORIGINAL  2   26
 REPEAT    2   28  29  30  31

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