| Entry |
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| Name |
Lomefloxacin hydrochloride (JAN/USAN);
LFLX;
Maxaquin (TN)
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| Formula |
C17H19F2N3O3. HCl
|
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| Exact mass |
387.1161
|
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| Mol weight |
387.8088
|
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| Structure |
     |
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| Activity |
Antibacterial
|
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| Remark |
Same as: Therapeutic category: ATC code: |
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| Target |
|
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| Interaction |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D00873 Lomefloxacin hydrochloride (JAN/USAN)
132 Otic and nasal agents
1329 Others
D00873 Lomefloxacin hydrochloride (JAN/USAN)
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
624 Synthetic antibacterials
6241 Pyridonecarboxylic acids
D00873 Lomefloxacin hydrochloride (JAN/USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA07 Lomefloxacin
D00873 Lomefloxacin hydrochloride (JAN/USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE04 Lomefloxacin
D00873 Lomefloxacin hydrochloride (JAN/USAN)
Antiinfectives [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor [KO:K02469 K02470 K02621 K02622]
Fluoroquinolones
Lomefloxacin [ATC:J01MA07]
D00873 Lomefloxacin hydrochloride (JAN/USAN)
 |
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| Other DBs |
CAS: 98079-52-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 26
1 C8y C 21.5092 -15.7765
2 C8y C 21.5092 -14.3792
3 N4y N 22.7668 -16.4751
4 C8y C 20.2983 -16.4751
5 C8y C 22.7668 -13.6806
6 C8x C 20.2983 -13.6806
7 C8x C 23.9777 -15.7765
8 C1b C 22.7668 -17.8724
9 C8y C 19.0872 -15.8230
10 X F 20.2983 -17.8724
11 C8y C 23.9777 -14.3792
12 O5x O 22.7668 -12.2833
13 C8y C 19.0872 -14.4257
14 N1y N 17.8763 -16.5216
15 C6a C 25.1888 -13.6806
16 X F 17.8763 -13.7738
17 C1x C 17.8763 -17.9189
18 C1x C 16.6653 -15.8696
19 O6a O 25.1888 -12.2833
20 O6a O 26.3997 -14.3792
21 C1y C 16.6653 -18.6642
22 C1x C 15.4543 -16.5682
23 N1x N 15.4543 -17.9655
24 C1a C 16.6653 -20.0615
25 C1a C 21.5568 -18.5713
26 X Cl 28.7751 -15.9627
BOND 27
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 4 10 1
10 5 11 1
11 5 12 2
12 6 13 2
13 9 14 1
14 11 15 1
15 13 16 1
16 14 17 1
17 14 18 1
18 15 19 2
19 15 20 1
20 17 21 1
21 18 22 1
22 21 23 1
23 21 24 1
24 7 11 2
25 9 13 1
26 22 23 1
27 8 25 1
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