KEGG   DRUG: D00874Help
Entry
D00874                      Drug                                   
Name
Moxifloxacin hydrochloride (JAN/USAN);
MFLX;
Avelox (TN);
Vigamox (TN)
Product
Formula
C21H24FN3O4. HCl
Exact mass
437.1518
Mol weight
437.8923
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Target
DNA gyrase inhibitor [KO:K02469 K02470];
topoisomerase IV inhibitor [KO:K02621] [KO:K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00874  Moxifloxacin hydrochloride (JAN/USAN)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6241  Pyridonecarboxylic acids
     D00874  Moxifloxacin hydrochloride (JAN/USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA14 Moxifloxacin
      D00874  Moxifloxacin hydrochloride (JAN/USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE07 Moxifloxacin
      D00874  Moxifloxacin hydrochloride (JAN/USAN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Moxifloxacin
    D00874  Moxifloxacin hydrochloride (JAN/USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor [KO:K02469 K02470 K02621 K02622]
    Fluoroquinolones
     Moxifloxacin [ATC:J01MA14]
      D00874  Moxifloxacin hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
186826-86-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   X   Cl   39.9355  -16.7249
            2   C8y C    32.2736  -16.4441
            3   N4y N    33.4897  -17.1398
            4   C8y C    31.0635  -17.1457
            5   C8y C    32.2678  -15.0467
            6   C1y C    33.4780  -18.5430
            7   C8x C    34.6940  -16.4324
            8   C8y C    29.8533  -16.4441
            9   O2a O    31.0518  -18.5430
            10  C8y C    33.4780  -14.3394
            11  C8x C    31.0635  -14.3452
            12  C1x C    34.1679  -19.7590
            13  C1x C    32.7648  -19.7415
            14  C8y C    34.6883  -15.0350
            15  N1y N    28.6665  -17.3387
            16  C8y C    29.8533  -15.0467
            17  C1a C    29.8357  -19.2446
            18  O5x O    33.4604  -12.9479
            19  C6a C    35.8926  -14.3394
            20  C1x C    27.8303  -16.2102
            21  C1x C    27.8537  -18.4787
            22  X   F    28.6371  -14.3511
            23  O6a O    37.0970  -15.0467
            24  O6a O    35.8868  -12.9422
            25  C1y C    26.5031  -16.6605
            26  C1y C    26.5148  -18.0518
            27  C1x C    25.2929  -15.9706
            28  N1x N    25.3163  -18.7534
            29  C1x C    24.0944  -16.6779
            30  C1x C    24.1061  -18.0694
BOND        33
            1     2   3 1
            2     2   4 2
            3     2   5 1
            4     3   6 1
            5     3   7 1
            6     4   8 1
            7     4   9 1
            8     5  10 1
            9     5  11 2
            10    6  12 1
            11    6  13 1
            12    7  14 2
            13    8  15 1
            14    8  16 2
            15    9  17 1
            16   10  18 2
            17   14  19 1
            18   15  20 1
            19   15  21 1
            20   16  22 1
            21   19  23 1
            22   19  24 2
            23   20  25 1
            24   21  26 1
            25   25  27 1
            26   26  28 1
            27   27  29 1
            28   28  30 1
            29   10  14 1
            30   11  16 1
            31   12  13 1
            32   25  26 1
            33   29  30 1

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