KEGG   DRUG: D00877Help
Entry
D00877                      Drug                                   

Name
Cycloserine (JP16/USP/INN);
Seromycin (TN)
Product
  Generic
Formula
C3H6N2O2
Exact mass
102.0429
Mol weight
102.0919
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Streptomyces lavendulae [TAX:1914] , Streptomyces roseochromogenes [TAX:67357]
Activity
Antibacterial [tuberculostatic] [DS:H00342]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Comment
Natural product
Target
D-alanine-D-alanine ligase inhibitor, cell wall synthesis inhibitor [KO:K01921];
alanine racemase inhibitor, cell wall synthesis inhibitor [KO:K01775]
  Pathway
ko00473  D-Alanine metabolism
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AB Antibiotics
     J04AB01 Cycloserine
      D00877  Cycloserine (JP16/USP/INN)
USP drug classification [BR:br08302]
 Antimycobacterials
  Antituberculars
   Cycloserine
    D00877  Cycloserine (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   616  Acting mainly on acid-fast bacteria
    6162  Cycloserines
     D00877  Cycloserine (JP16/USP/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Others
    alanine racemase inhibitor
     Cycloserine
      D00877  Cycloserine (JP16/USP/INN)
    D-alanine-D-alanine ligase inhibitor
     Cycloserine
      D00877  Cycloserine (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00877  Cycloserine
BRITE hierarchy
Other DBs
CAS: 
68-41-7
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        7
            1   C1x C     7.7000  -17.0800
            2   O2x O     9.1000  -17.0800
            3   N1x N     9.5326  -15.7485
            4   C5x C     8.4000  -14.9256
            5   C1y C     7.2674  -15.7485
            6   O5x O     8.4000  -13.5100
            7   N1a N     5.9478  -15.3197
BOND        7
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     4   6 2
            7     5   7 1 #Up

» Japanese version   » Back

DBGET integrated database retrieval system