KEGG   DRUG: D00905Help
Entry
D00905                      Drug                                   

Name
Cefazolin sodium (JP16/USP);
Ancef (TN)
Product
  Generic
CEFAZOLIN (APP Pharmaceuticals), CEFAZOLIN (Apotex Corp), CEFAZOLIN (Apotex Corp), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (Cardinal Health), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (Hospira), CEFAZOLIN (Hospira), CEFAZOLIN (Hospira), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (Sandoz), CEFAZOLIN (WG Critical Care), CEFAZOLIN (WG Critical Care), CEFAZOLIN (West-Ward Pharmaceutical Corp), CEFAZOLIN (West-Ward Pharmaceutical Corp), CEFAZOLIN (APP Pharmaceuticals), CEFAZOLIN (APP Pharmaceuticals), CEFAZOLIN (Baxter Healthcare Corporation), CEFAZOLIN (Dispensing Solutions), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (General Injectables & Vaccines), CEFAZOLIN (Physicians Total Care), CEFAZOLIN (Sagent Pharmaceuticals), CEFAZOLIN (Sagent Pharmaceuticals), CEFAZOLIN (Samson Medical Technologies)
  Other
Formula
C14H13N8O4S3. Na
Exact mass
476.012
Mol weight
476.489
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial [systemic]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB04 Cefazolin
      D00905  Cefazolin sodium (JP16/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefazolin
    D00905  Cefazolin sodium (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D00905  Cefazolin sodium (JP16/USP)
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   729  Miscellaneous
    7290  Miscellaneous
     D00905  Cefazolin sodium (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefazolin
      D00905  Cefazolin sodium (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00905  Cefazolin sodium
  D00905  Cefazolin sodium for injection
BRITE hierarchy
Other DBs
CAS: 
27164-46-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C1y C    18.0487  -14.7849
            2   N1y N    18.0487  -16.1806
            3   C2y C    19.2576  -16.8783
            4   C2y C    20.4663  -16.1806
            5   C1x C    20.4663  -14.7849
            6   S2x S    19.2576  -14.0870
            7   C1y C    16.6529  -14.7849
            8   C5x C    16.6529  -16.1806
            9   N1b N    15.4443  -14.0870
            10  C5a C    14.2354  -14.7849
            11  O5a O    14.2354  -16.1806
            12  O5x O    15.4443  -16.8783
            13  C1b C    13.0266  -14.0870
            14  C1b C    21.6935  -16.8895
            15  C6a C    19.2576  -18.2739
            16  O6a O    18.0319  -18.9816
            17  O6a O    20.4493  -18.9621 #-
            18  N4y N    11.7985  -14.7965
            19  S2a S    22.9071  -16.1890
            20  C8y C    24.1155  -16.8870
            21  N5x N    24.5393  -18.2151
            22  N5x N    25.9360  -18.2265
            23  C8y C    26.3784  -16.9017
            24  S2x S    25.2552  -16.0715
            25  C1a C    27.7744  -16.8829
            26  C8x C    10.6469  -13.9856
            27  N5x N     9.5153  -14.8305
            28  N5x N     9.9690  -16.1679
            29  N5x N    11.3811  -16.1498
            30  Z   Na   21.9094  -18.8997 #+
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   14  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   20  24 1
            27   23  25 1
            28   18  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   18  29 1

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