KEGG   DRUG: D00906Help
Entry
D00906                      Drug                                   
Name
Cephalexin (USP);
Cephalexin monohydrate;
Cefalexin;
CEX;
Keftab (TN);
Panixine disperdose (TN)
Product
  Generic
CEPHALEXIN (Aidarex Pharmaceuticals LLC), CEPHALEXIN (Aidarex Pharmaceuticals LLC), CEPHALEXIN (Altura Pharmaceuticals), CEPHALEXIN (American Antibiotics), CEPHALEXIN (Ascend Laboratories), CEPHALEXIN (Aurobindo Pharma Limited), CEPHALEXIN (AvKARE), CEPHALEXIN (Belcher Pharmaceuticals), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Carlsbad Technology), CEPHALEXIN (Carlsbad Technology), CEPHALEXIN (Dispensing Solutions), CEPHALEXIN (Gen-Source Rx), CEPHALEXIN (Gen-Source Rx), CEPHALEXIN (Golden State Medical Supply), CEPHALEXIN (Golden State Medical Supply), CEPHALEXIN (H.J. Harkins Company), CEPHALEXIN (H.J. Harkins Company), CEPHALEXIN (H.J. Harkins Company), CEPHALEXIN (Jazeera Pharmaceutical), CEPHALEXIN (Karalex Pharma LLC), CEPHALEXIN (Karalex Pharma LLC), CEPHALEXIN (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), CEPHALEXIN (Lupin Pharmaceuticals), CEPHALEXIN (Lupin Pharmaceuticals), CEPHALEXIN (NorthStar Rx LLC), CEPHALEXIN (OrchidPharma), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (Physicians Total Care), CEPHALEXIN (Physicians Total Care), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp.), CEPHALEXIN (RedPharm Drug), CEPHALEXIN (STAT RX USA LLC), CEPHALEXIN (STAT RX USA LLC), CEPHALEXIN (STAT Rx USA LLC), CEPHALEXIN (State of Florida DOH Central Pharmacy), CEPHALEXIN (Strategic Pharmaceutical Solutions), CEPHALEXIN (Sun Pharmaceutical Industries Limited), CEPHALEXIN (Teva Pharmaceuticals USA), CEPHALEXIN (Unit Dose Services), CEPHALEXIN (Virtus Pharmaceuticals), CEPHALEXIN (West-ward Pharmaceutical Corp), CEPHALEXIN (West-ward Pharmaceutical Corp)
Formula
C16H17N3O4S. H2O
Exact mass
365.1045
Mol weight
365.4042
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Metabolism
Transporter: SLC15A1 [HSA:6564], SCL15A2 [HSA:6565]
Structure map
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB01 Cefalexin
      D00906  Cephalexin (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cephalosporin Antibacterials, 1st Generation
    Cephalexin
     D00906  Cephalexin (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefalexin [ATC:J01DB01]
      D00906  Cephalexin (USP)
BRITE hierarchy
Other DBs
CAS: 
23325-78-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1y C    29.3164  -14.8915
            2   N1y N    29.3164  -16.2906
            3   C2y C    30.5281  -16.9900
            4   C2y C    31.7398  -16.2906
            5   C1x C    31.7398  -14.8915
            6   S2x S    30.5281  -14.1919
            7   C1y C    27.9173  -14.8915
            8   C5x C    27.9173  -16.2906
            9   N1b N    26.7057  -14.1919
            10  C5a C    25.4938  -14.8915
            11  O5a O    25.4938  -16.2906
            12  O5x O    26.7057  -16.9900
            13  C1c C    24.2822  -14.1919
            14  C1a C    32.9701  -17.0012
            15  C6a C    30.5281  -18.3890
            16  O6a O    29.2996  -19.0984
            17  O6a O    31.7228  -19.0789
            18  C8y C    23.0510  -14.9031
            19  C8x C    21.8409  -14.2044
            20  C8x C    20.6307  -14.9031
            21  C8x C    20.6307  -16.3005
            22  C8x C    21.8409  -16.9992
            23  C8x C    23.0510  -16.3005
            24  N1a N    24.2822  -12.7883
            25  O0  O    34.7200  -15.0500
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up

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