KEGG   DRUG: CephalexinHelp
Entry
D00906                      Drug                                   

Name
Cephalexin (USP);
Cephalexin monohydrate;
Cefalexin;
CEX;
Keftab (TN);
Panixine disperdose (TN)
Product
  Generic
CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (A-S Medication Solutions LLC), CEPHALEXIN (Aidarex Pharmaceuticals LLC), CEPHALEXIN (Aidarex Pharmaceuticals LLC), CEPHALEXIN (Altura Pharmaceuticals), CEPHALEXIN (American Antibiotics), CEPHALEXIN (American Health Packaging), CEPHALEXIN (Apotheca), CEPHALEXIN (Ascend Laboratories), CEPHALEXIN (Aurobindo Pharma Limited), CEPHALEXIN (AvKARE), CEPHALEXIN (AvPAK), CEPHALEXIN (Avera McKennan Hospital), CEPHALEXIN (Belcher Pharmaceuticals), CEPHALEXIN (Bi-Coastal Pharma International LLC), CEPHALEXIN (Blenheim Phamacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Blenheim Pharmacal), CEPHALEXIN (Cardinal Health), CEPHALEXIN (Carlsbad Technology), CEPHALEXIN (Carlsbad Technology), CEPHALEXIN (DIRECT RX), KEFLEX (DIRECT RX), KEFLEX (DIRECT RX), KEFLEX (DIRECT RX), CEPHALEXIN (DIRECT RX), CEPHALEXIN (DIRECT RX), CEPHALEXIN (DirectRX), CEPHALEXIN (Dispensing Solutions), CEPHALEXIN (Gen-Source Rx), CEPHALEXIN (Golden State Medical Supply), CEPHALEXIN (Golden State Medical Supply), CEPHALEXIN (H.J. Harkins Company), CEPHALEXIN (H.J. Harkins Company), CEPHALEXIN (H.J. Harkins Company), CEPHALEXIN (Jazeera Pharmaceutical), CEPHALEXIN (LUPIN LIMITED), CEPHALEXIN (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), CEPHALEXIN (Lake Erie Medical DBA Quality Care Products LLC), CEPHALEXIN (Lake Erie Medical DBA Quality Care Products LLC), CEPHALEXIN (Lake Erie Medical DBA Quality Care Products LLC), CEPHALEXIN (Lake Erie Medical DBA Quality Care Products LLC), CEPHALEXIN (Lake Erie Medical DBA Quality Care Products LLC), CEPHALEXIN (Liberty Pharmaceuticals), CEPHALEXIN (Liberty Pharmaceuticals), CEPHALEXIN (Lupin Pharmaceuticals), CEPHALEXIN (Lupin Pharmaceuticals), CEPHALEXIN (MedVantx), CEPHALEXIN (MedVantx), CEPHALEXIN (MedVantx), CEPHALEXIN (MedVantx), CEPHALEXIN (MedVantx), CEPHALEXIN (Medsource Pharmaceuticals), CEPHALEXIN (Northwind Pharmaceuticals), CEPHALEXIN (Northwind Pharmaceuticals), CEPHALEXIN (Northwind Pharmaceuticals), CEPHALEXIN (Northwind Pharmaceuticals), CEPHALEXIN (OrchidPharma), CEPHALEXIN (OrchidPharma), CEPHALEXIN (OrchidPharma), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (PD-Rx Pharmaceuticals), CEPHALEXIN (Physicians Total Care), CEPHALEXIN (Physicians Total Care), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Preferred Pharmaceuticals), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (Proficient Rx LP), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (REMEDYREPACK), CEPHALEXIN (ReadyMeds), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp), CEPHALEXIN (Rebel Distributors Corp.), CEPHALEXIN (RedPharm Drug), CEPHALEXIN (STAT RX USA LLC), CEPHALEXIN (STAT RX USA LLC), CEPHALEXIN (STAT Rx USA LLC), CEPHALEXIN (State of Florida DOH Central Pharmacy), CEPHALEXIN (State of Florida DOH Central Pharmacy), CEPHALEXIN (State of Florida DOH Central Pharmacy), CEPHALEXIN (Strategic Pharmaceutical Solutions), CEPHALEXIN (Sun Pharmaceutical Industries Limited), CEPHALEXIN (TYA Pharmaceuticals), CEPHALEXIN (TYA Pharmaceuticals), CEPHALEXIN (TYA Pharmaceuticals), CEPHALEXIN (Teva Pharmaceuticals USA), CEPHALEXIN (Unit Dose Services), CEPHALEXIN (Unit Dose Services), CEPHALEXIN (Unit Dose Services), CEPHALEXIN (Unit Dose Services), CEPHALEXIN (Virtus Pharmaceuticals), CEPHALEXIN (Virtus Pharmaceuticals), CEPHALEXIN (West-ward Pharmaceutical Corp), CEPHALEXIN (West-ward Pharmaceutical Corp)
Formula
C16H17N3O4S. H2O
Exact mass
365.1045
Mol weight
365.4042
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01774  First-generation cephalosporin
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antibacterial, Cell wall biosynthesis inhibitor
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding protein
  Pathway
Peptidoglycan biosynthesis
Metabolism
Transporter: SLC15A1 [HSA:6564], SCL15A2 [HSA:6565]
Interaction
Drug interaction
Structure map
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB01 Cefalexin
      D00906  Cephalexin (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cephalexin
    D00906  Cephalexin (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephem
     First-generation cephalosporin
      Cefalexin
       D00906  Cephalexin (USP)
Cytochrome P450 interactions [BR:br08309]
 Transporter substrates
  SLC15A1
   Cefalexin
    D00906  Cephalexin (USP)
  SCL15A2
   Cefalexin
    D00906  Cephalexin (USP)
  MATE1
   Cefalexin
    D00906  Cephalexin (USP)
  MATE2
   Cefalexin
    D00906  Cephalexin (USP)
Antibacterials [br08350.html]
 D00906
BRITE hierarchy
Other DBs
CAS: 
23325-78-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1y C    29.3164  -14.8915
            2   N1y N    29.3164  -16.2906
            3   C2y C    30.5281  -16.9900
            4   C2y C    31.7398  -16.2906
            5   C1x C    31.7398  -14.8915
            6   S2x S    30.5281  -14.1919
            7   C1y C    27.9173  -14.8915
            8   C5x C    27.9173  -16.2906
            9   N1b N    26.7057  -14.1919
            10  C5a C    25.4938  -14.8915
            11  O5a O    25.4938  -16.2906
            12  O5x O    26.7057  -16.9900
            13  C1c C    24.2822  -14.1919
            14  C1a C    32.9701  -17.0012
            15  C6a C    30.5281  -18.3890
            16  O6a O    29.2996  -19.0984
            17  O6a O    31.7228  -19.0789
            18  C8y C    23.0510  -14.9031
            19  C8x C    21.8409  -14.2044
            20  C8x C    20.6307  -14.9031
            21  C8x C    20.6307  -16.3005
            22  C8x C    21.8409  -16.9992
            23  C8x C    23.0510  -16.3005
            24  N1a N    24.2822  -12.7883
            25  O0  O    34.7200  -15.0500
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up

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