KEGG   DRUG: D00915Help
Entry
D00915                      Drug                                   

Name
Cefuroxime sodium (JAN/USP);
CXM;
Zinacef (TN)
Product
  Generic
Formula
C16H15N4O8S. Na
Exact mass
446.0508
Mol weight
446.3671
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Comment
Semisynthetic cephalosporin: intermediate spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC02 Cefuroxime
      D00915  Cefuroxime sodium (JAN/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA27 Cefuroxime
      D00915  Cefuroxime sodium (JAN/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefuroxime
    D00915  Cefuroxime sodium (JAN/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefuroxime [ATC:J01DC02]
      D00915  Cefuroxime sodium (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
56238-63-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C1y C    32.5439  -17.8678
            2   N1y N    32.5439  -19.2637
            3   C2y C    33.7531  -19.9616
            4   C2y C    34.9620  -19.2637
            5   C1x C    34.9620  -17.8678
            6   S2x S    33.7531  -17.1697
            7   C1y C    31.1478  -17.8678
            8   C5x C    31.1478  -19.2637
            9   N1b N    29.9390  -17.1697
            10  C5a C    28.7299  -17.8678
            11  O5a O    28.7299  -19.2637
            12  O5x O    29.9390  -19.9616
            13  C2c C    27.5208  -17.1697
            14  C1b C    36.1894  -19.9728
            15  C6a C    33.7531  -21.3574
            16  O6a O    32.5271  -22.0653
            17  O6a O    34.9450  -22.0458 #-
            18  C8y C    26.2925  -17.8794
            19  O2x O    25.1407  -17.0683
            20  C8x C    24.0088  -17.9134
            21  C8x C    24.4626  -19.2510
            22  C8x C    25.8750  -19.2329
            23  N2b N    27.5207  -15.7524
            24  O7a O    37.4156  -19.2654
            25  C7a C    38.6006  -19.9502
            26  N1a N    39.7939  -19.2616
            27  O6a O    38.6002  -21.3533
            28  O2a O    28.7261  -15.0563
            29  C1a C    28.7261  -13.6563
            30  Z   Na   36.2600  -21.9800 #+
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   18  22 2
            25   13  23 2
            26   14  24 1
            27   24  25 1
            28   25  26 1
            29   25  27 2
            30   23  28 1
            31   28  29 1

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