| Entry |
|
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| Name |
Cefuroxime sodium (JAN/USP);
CXM;
Zinacef (TN)
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| Product |
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| Generic |
CEFUROXIME (APP Pharmaceuticals), CEFUROXIME (APP Pharmaceuticals), CEFUROXIME (Hospira), CEFUROXIME (Hospira), CEFUROXIME (WG Critical Care), CEFUROXIME (WG Critical Care), CEFUROXIME (West-ward Pharmaceutical Corp), CEFUROXIME (West-ward Pharmaceutical Corp), CEFUROXIME SODIUM (Sagent Pharmaceuticals), CEFUROXIME (Sagent Pharmaceuticals), CEFUROXIME SODIUM (Samson Medical Technologies) |
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| Formula |
C16H15N4O8S. Na
|
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| Exact mass |
446.0508
|
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| Mol weight |
446.3671
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| Structure |
     |
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| Activity |
Antibacterial
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| Remark |
|
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| Comment |
Semisynthetic cephalosporin: intermediate spectrum cephalosporin
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| Target |
penicillin binding proteins inhibitor |
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| Pathway |
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| Interaction |
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| Structure map |
| Cephalosporins - parenteral agents |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC02 Cefuroxime
D00915 Cefuroxime sodium (JAN/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA27 Cefuroxime
D00915 Cefuroxime sodium (JAN/USP)
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cephalosporin Antibacterials, 2nd Generation
Cefuroxime
D00915 Cefuroxime sodium (JAN/USP)
Antiinfectives [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor
Penicillin binding proteins inhibitor
Cephems - Cephalosporins
Cefuroxime [ATC:J01DC02]
D00915 Cefuroxime sodium (JAN/USP)
 |
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| Other DBs |
CAS: 56238-63-2 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 30
1 C1y C 32.5439 -17.8678
2 N1y N 32.5439 -19.2637
3 C2y C 33.7531 -19.9616
4 C2y C 34.9620 -19.2637
5 C1x C 34.9620 -17.8678
6 S2x S 33.7531 -17.1697
7 C1y C 31.1478 -17.8678
8 C5x C 31.1478 -19.2637
9 N1b N 29.9390 -17.1697
10 C5a C 28.7299 -17.8678
11 O5a O 28.7299 -19.2637
12 O5x O 29.9390 -19.9616
13 C2c C 27.5208 -17.1697
14 C1b C 36.1894 -19.9728
15 C6a C 33.7531 -21.3574
16 O6a O 32.5271 -22.0653
17 O6a O 34.9450 -22.0458 #-
18 C8y C 26.2925 -17.8794
19 O2x O 25.1407 -17.0683
20 C8x C 24.0088 -17.9134
21 C8x C 24.4626 -19.2510
22 C8x C 25.8750 -19.2329
23 N2b N 27.5207 -15.7524
24 O7a O 37.4156 -19.2654
25 C7a C 38.6006 -19.9502
26 N1a N 39.7939 -19.2616
27 O6a O 38.6002 -21.3533
28 O2a O 28.7261 -15.0563
29 C1a C 28.7261 -13.6563
30 Z Na 36.2600 -21.9800 #+
BOND 31
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 3 15 1
17 15 16 2
18 15 17 1
19 13 18 1
20 18 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 18 22 2
25 13 23 2
26 14 24 1
27 24 25 1
28 25 26 1
29 25 27 2
30 23 28 1
31 28 29 1
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