KEGG   DRUG: D00920Help
Entry
D00920                      Drug                                   

Name
Cefpodoxime proxetil (JP16/USP);
CPDX-PR;
Vantin (TN)
Product
  Generic
Formula
C21H27N5O9S2
Exact mass
557.125
Mol weight
557.5972
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
prodrug, active substance: Cefpodoxime [DR:D07650]
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD13 Cefpodoxime
      D00920  Cefpodoxime proxetil (JP16/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefpodoxime
    D00920  Cefpodoxime proxetil (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D00920  Cefpodoxime proxetil (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefpodoxime
      D00920  Cefpodoxime proxetil (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00920  Cefpodoxime proxetil
  D00920  Cefpodoxime proxetil tablets
BRITE hierarchy
Other DBs
CAS: 
87239-81-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        37
            1   C1y C    31.5842  -17.3805
            2   N1y N    31.5842  -18.7567
            3   C2y C    32.7540  -19.4449
            4   C2y C    33.9239  -18.7567
            5   C1x C    33.9239  -17.3805
            6   S2x S    32.7540  -16.6923
            7   C1y C    30.2079  -17.3805
            8   C5x C    30.2079  -18.7567
            9   N1b N    28.9691  -16.6923
            10  C5a C    27.7993  -17.3805
            11  O5a O    27.7993  -18.7567
            12  O5x O    28.9691  -19.4449
            13  C2c C    26.6294  -16.6923
            14  C1b C    35.1627  -19.4449
            15  C8y C    25.3906  -17.3805
            16  C8x C    24.3584  -16.5546
            17  S2x S    23.1886  -17.3116
            18  C8y C    23.6015  -18.6879
            19  N5x N    24.9777  -18.6879
            20  N2b N    26.6294  -15.3158
            21  C7a C    32.7540  -21.7845
            22  O7a O    33.9239  -22.4727
            23  O6a O    31.5154  -22.4727
            24  N1a N    22.7757  -19.7889
            25  O2a O    36.3407  -18.7387
            26  C1a C    37.5407  -19.4054
            27  C1c C    35.1193  -21.7954
            28  O7a O    36.2775  -22.4768
            29  C1a C    35.0621  -20.4067
            30  C7a C    37.4637  -21.8047
            31  O7a O    38.6645  -22.5115
            32  C1c C    39.8522  -21.8393
            33  O6a O    37.4747  -20.4063
            34  C1a C    41.0316  -22.5338
            35  C1a C    39.8639  -20.4752
            36  O2a O    27.8164  -14.6368
            37  C1a C    27.8164  -13.2368
BOND        39
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16   13  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 1
            20   18  19 2
            21   15  19 1
            22   13  20 2
            23    3  21 1
            24   21  22 1
            25   21  23 2
            26   18  24 1
            27   14  25 1
            28   25  26 1
            29   22  27 1
            30   27  28 1
            31   27  29 1
            32   28  30 1
            33   30  31 1
            34   31  32 1
            35   30  33 2
            36   32  34 1
            37   32  35 1
            38   20  36 1
            39   36  37 1

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