KEGG   DRUG: D00921Help
Entry
D00921                      Drug                                   

Name
Ceftazidime hydrate (JP16);
Ceftazidime (USP);
Ceftazidime pentahydrate;
CAZ;
Fortaz (TN);
Tazicef (TN)
Product
  Generic
Formula
C22H22N6O7S2. 5H2O
Exact mass
636.152
Mol weight
636.6525
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD02 Ceftazidime
      D00921  Ceftazidime hydrate (JP16); Ceftazidime (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Ceftazidime
    D00921  Ceftazidime hydrate (JP16); Ceftazidime (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D00921  Ceftazidime hydrate (JP16); Ceftazidime (USP)
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   729  Miscellaneous
    7290  Miscellaneous
     D00921  Ceftazidime hydrate (JP16); Ceftazidime (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Ceftazidime
      D00921  Ceftazidime hydrate (JP16); Ceftazidime (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00921  Ceftazidime hydrate
  D00921  Ceftazidime for injection
BRITE hierarchy
Other DBs
CAS: 
78439-06-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        42
            1   C1y C    32.7600  -19.2500
            2   N1y N    32.7600  -20.6500
            3   C2y C    33.9500  -21.3500
            4   C2y C    35.1400  -20.6500
            5   C1x C    35.1400  -19.2500
            6   S2x S    33.9500  -18.5500
            7   C1y C    31.3600  -19.2500
            8   C5x C    31.3600  -20.6500
            9   N1b N    30.1000  -18.5500
            10  C5a C    28.9100  -19.2500
            11  O5a O    28.9100  -20.6500
            12  O5x O    30.1000  -21.3500
            13  C2c C    27.7200  -18.5500
            14  C1b C    36.4000  -21.3500
            15  C8y C    26.4600  -19.2500
            16  C8x C    25.4100  -18.4100
            17  S2x S    24.2200  -19.1800
            18  C8y C    24.6400  -20.5800
            19  N5x N    26.0400  -20.5800
            20  N2b N    27.7200  -17.1500
            21  C6a C    33.9500  -22.7500
            22  O6a O    35.1400  -23.4500 #-
            23  O6a O    32.6900  -23.4500
            24  N1a N    23.8000  -21.7000
            25  N5y N    37.5900  -20.5800 #+
            26  C8x C    38.7800  -21.2800
            27  C8x C    39.9700  -20.5800
            28  C8x C    39.9700  -19.1800
            29  C8x C    38.7800  -18.4800
            30  C8x C    37.5900  -19.1800
            31  O2a O    28.9100  -16.4500
            32  C1d C    28.9100  -15.0500
            33  C1a C    28.9100  -13.6500
            34  C6a C    30.3100  -15.0500
            35  C1a C    27.5100  -15.0500
            36  O6a O    31.0100  -16.2400
            37  O6a O    31.0100  -13.8600
            38  O0  O    27.7200  -22.8200
            39  O0  O    27.7200  -22.8200
            40  O0  O    27.7200  -22.8200
            41  O0  O    27.7200  -22.8200
            42  O0  O    27.7200  -22.8200
BOND        40
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16   13  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 1
            20   18  19 2
            21   15  19 1
            22   13  20 2
            23    3  21 1
            24   21  22 1
            25   21  23 2
            26   18  24 1
            27   14  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   28  29 1
            32   29  30 2
            33   25  30 1
            34   20  31 1
            35   31  32 1
            36   32  33 1
            37   32  34 1
            38   32  35 1
            39   34  36 1
            40   34  37 2
BRACKET     1    25.6200  -23.4500   25.6200  -22.0500
            1    28.2100  -22.0500   28.2100  -23.4500
            1  5
 ORIGINAL  1   39
 REPEAT    1   40  41  42  43

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