KEGG   DRUG: D00923Help
Entry
D00923                      Drug                                   

Name
Ceftizoxime sodium (JP16/USP);
CZX;
Cefizox (TN);
Epocelin (TN)
Formula
C13H12N5O5S2. Na
Exact mass
405.0178
Mol weight
405.3846
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Metabolism
Transporter: SLC22A8 [HSA:9376]
Interaction
Drug interaction
Structure map
Cephalosporins - parenteral agents
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD07 Ceftizoxime
      D00923  Ceftizoxime sodium (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D00923  Ceftizoxime sodium (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Ceftizoxime
      D00923  Ceftizoxime sodium (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00923  Ceftizoxime sodium
BRITE hierarchy
Other DBs
CAS: 
68401-82-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C1y C    27.6266  -18.8498
            2   N1y N    27.6266  -20.2389
            3   C2y C    28.8298  -20.9335
            4   C2x C    30.0328  -20.2389
            5   C1x C    30.0328  -18.8498
            6   S2x S    28.8298  -18.1552
            7   C1y C    26.2373  -18.8498
            8   C5x C    26.2373  -20.2389
            9   N1b N    25.0345  -18.1552
            10  C5a C    23.8313  -18.8498
            11  O5a O    23.8313  -20.2389
            12  O5x O    25.0345  -20.9335
            13  C2c C    22.6281  -18.1552
            14  C8y C    21.4059  -18.8613
            15  C8x C    20.2754  -18.0309
            16  S2x S    19.1316  -18.8479
            17  C8y C    19.5551  -20.2580
            18  N5x N    20.9606  -20.2695
            19  N2b N    22.6280  -16.7447
            20  C6a C    28.8298  -22.3394
            21  O6a O    30.0435  -23.0401 #-
            22  O6a O    27.6177  -23.0393
            23  N1a N    18.7515  -21.3864
            24  O2a O    23.8330  -16.0487
            25  C1a C    23.8333  -14.6304
            26  Z   Na   31.5041  -22.9885 #+
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 1
            19   17  18 2
            20   14  18 1
            21   13  19 2
            22    3  20 1
            23   20  21 1
            24   20  22 2
            25   17  23 1
            26   19  24 1
            27   24  25 1

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