| Entry |
|
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| Name |
Pioglitazone hydrochloride (JP16/USP);
Actos (TN)
|
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| Product |
|
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| Generic |
PIOGLITAZONE (Mylan Institutional), PIOGLITAZONE (Mylan Pharmaceuticals), PIOGLITAZONE (Ranbaxy Pharmaceuticals), PIOGLITAZONE (Ranbaxy Pharmaceuticals), PIOGLITAZONE (Sandoz), PIOGLITAZONE (Teva Pharmaceuticals USA), PIOGLITAZONE HYDROCHLORIDE (Accord Healthcare), PIOGLITAZONE HYDROCHLORIDE (American Health Packaging), PIOGLITAZONE HYDROCHLORIDE (Aurobindo Pharma Limited), PIOGLITAZONE HYDROCHLORIDE (Breckenridge Pharmaceutical), PIOGLITAZONE HYDROCHLORIDE (Watson Laboratories), PIOGLITAZONEHYDROCHLORIDE (Torrent Pharmaceuticals Limited) |
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| Formula |
C19H20N2O3S. HCl
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| Exact mass |
392.0961
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| Mol weight |
392.8996
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| Structure |
     |
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| Activity |
|
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| Remark |
Therapeutic category: ATC code: |
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| Target |
peroxisome proliferator-activated receptor (PPAR) gamma agonist [HSA: 5468] [KO: K08530] |
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| Pathway |
|
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| Interaction |
CYP induction: CYP3A [KO: K07424]
 |
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| Structure map |
| Antidiabetics | | Peroxisome proliferator-activated receptor (PPAR) agonists |
|
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
396 Antidiabetic agents
3969 Others
D00945 Pioglitazone hydrochloride (JP16/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BG Thiazolidinediones
A10BG03 Pioglitazone
D00945 Pioglitazone hydrochloride (JP16/USP)
USP drug classification [BR:br08302]
Blood Glucose Regulators
Antidiabetic Agents
Thiazolidinediones
Pioglitazone
D00945 Pioglitazone hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
peroxisome proliferator-activated receptor (PPAR) gamma [HSA:5468] [KO:K08530]
Pioglitazone [ATC:A10BG03]
D00945 Pioglitazone hydrochloride (JP16/USP)
 |
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| Other DBs |
CAS: 112529-15-4 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 26
1 C1y C 36.4918 -16.3605
2 C1b C 35.2747 -15.6584
3 C5x C 36.5002 -17.7636
4 S2x S 37.8328 -15.9323
5 C8y C 34.0636 -16.3605
6 N1x N 37.8315 -18.1968
7 O5x O 35.3724 -18.5929
8 C5x C 38.6556 -17.0654
9 C8x C 32.8527 -15.6584
10 C8x C 34.0636 -17.7589
11 O5x O 40.0558 -17.0643
12 C8x C 31.6415 -16.3605
13 C8x C 32.8527 -18.4610
14 C8y C 31.6415 -17.7589
15 O2a O 30.4304 -18.4610
16 C1b C 29.2134 -17.7589
17 C1b C 28.0023 -18.4610
18 C8y C 26.7911 -17.7589
19 C8x C 26.7911 -16.3664
20 N5x N 25.5800 -18.4668
21 C8x C 25.5800 -15.6701
22 C8x C 24.3689 -17.7647
23 C8y C 24.3689 -16.3664
24 C1b C 23.1580 -15.6701
25 C1a C 21.9409 -16.3664
26 X Cl 42.2119 -18.3454
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 2
7 4 8 1
8 5 9 2
9 5 10 1
10 8 11 2
11 9 12 1
12 10 13 2
13 12 14 2
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 2
19 18 20 1
20 19 21 1
21 20 22 2
22 21 23 2
23 23 24 1
24 24 25 1
25 6 8 1
26 13 14 1
27 22 23 1
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