KEGG   DRUG: D00947Help
Entry
D00947                      Drug                                   

Name
Linezolid (JAN/USAN/INN);
Zyvox (TN)
Product
Formula
C16H20FN3O4
Exact mass
337.1438
Mol weight
337.3461
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Comment
Oxazolidinones
Target
50S ribosomal subunit, protein synthesis inhibitor
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX08 Linezolid
      D00947  Linezolid (JAN/USAN/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Linezolid
    D00947  Linezolid (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6249  Others
     D00947  Linezolid (JAN/USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   50S ribosomal subunit inhibitor
    Oxazolidinones
     Linezolid
      D00947  Linezolid (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
165800-03-3
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8x C    18.4100  -19.7400
            2   C8y C    18.4100  -18.3400
            3   C8y C    17.1500  -17.6400
            4   C8x C    15.9600  -18.3400
            5   C8y C    15.9600  -19.7400
            6   C8x C    17.1500  -20.4400
            7   N1y N    19.6000  -17.6400
            8   C1x C    20.7900  -18.3400
            9   C1x C    22.0500  -17.6400
            10  O2x O    22.0500  -16.2400
            11  C1x C    20.7900  -15.5400
            12  C1x C    19.6000  -16.2400
            13  X   F    17.1500  -16.2400
            14  N1y N    14.7000  -20.4400
            15  C1x C    13.3826  -19.9663
            16  C1y C    12.5634  -21.0931
            17  O7x O    13.3514  -22.2462
            18  C7x C    14.6895  -21.8347
            19  O6a O    15.7753  -22.7458
            20  C1b C    11.1300  -21.0728
            21  N1b N    10.4461  -19.8484
            22  C5a C     9.0310  -19.8980
            23  C1a C     8.2805  -18.6975
            24  O5a O     8.3810  -21.1205
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    7  12 1
            14    3  13 1
            15    5  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   14  18 1
            21   18  19 2
            22   16  20 1 #Up
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   22  24 2

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