KEGG   DRUG: LinezolidHelp
Entry
D00947                      Drug                                   

Name
Linezolid (JAN/USAN/INN);
Zyvox (TN)
Product
  Generic
LINEZOLID (Alembic Pharmaceuticals), LINEZOLID (Alembic Pharmaceuticals Limited), LINEZOLID (American Health Packaging), LINEZOLID (American Health Packaging), LINEZOLID (Amneal Pharmaceuticals LLC), LINEZOLID (Apotex Corp.), LINEZOLID (Ascend Laboratories), LINEZOLID (AuroMedics Pharma LLC), LINEZOLID (AvPAK), LINEZOLID (Cadila Healthcare Limited), LINEZOLID (Camber Pharmaceuticals), LINEZOLID (Fresenius Kabi Norge AS), LINEZOLID (Fresenius Kabi USA), LINEZOLID (Glenmark Pharmaceuticals), LINEZOLID (Greenstone LLC), LINEZOLID (Hospira), LINEZOLID (Major Pharmaceuticals), LINEZOLID (Mylan Institutional), LINEZOLID (Mylan Pharmaceuticals), LINEZOLID (Novel Laboratories), LINEZOLID (REMEDYREPACK), LINEZOLID (Sagent Pharmaceuticals), LINEZOLID (Sandoz), LINEZOLID (Sun Pharmaceutical Industries), LINEZOLID (Teva Parenteral Medicines), LINEZOLID (Teva Pharmaceuticals USA), LINEZOLID (Teva Pharmaceuticals USA), LINEZOLID (West-Ward Pharmaceuticals Corp.), LINEZOLID (Zydus Pharmaceuticals (USA))
Formula
C16H20FN3O4
Exact mass
337.1438
Mol weight
337.3461
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antibacterial
 DG01789  Oxazolidinone
Remark
Same as: 
Therapeutic category: 
ATC code: 
Chemical group: 
Efficacy
Antibacterial, Protein biosynthesis inhibitor
  Disease
Vancomycin-Resistant Enterococcus faecium infection [DS:H00340]
Comment
Oxazolidinones
Target
50S ribosomal subunit
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX08 Linezolid
      D00947  Linezolid (JAN/USAN/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Linezolid
    D00947  Linezolid (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6249  Others
     D00947  Linezolid (JAN/USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   50S subunit inhibitor
    Oxazolidinones
     Linezolid
      D00947  Linezolid (JAN/USAN/INN)
Antibacterials [br08350.html]
 D00947
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D00947
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00947
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00947
BRITE hierarchy
Other DBs
CAS: 
165800-03-3
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8x C    18.4100  -19.7400
            2   C8y C    18.4100  -18.3400
            3   C8y C    17.1500  -17.6400
            4   C8x C    15.9600  -18.3400
            5   C8y C    15.9600  -19.7400
            6   C8x C    17.1500  -20.4400
            7   N1y N    19.6000  -17.6400
            8   C1x C    20.7900  -18.3400
            9   C1x C    22.0500  -17.6400
            10  O2x O    22.0500  -16.2400
            11  C1x C    20.7900  -15.5400
            12  C1x C    19.6000  -16.2400
            13  X   F    17.1500  -16.2400
            14  N1y N    14.7000  -20.4400
            15  C1x C    13.3826  -19.9663
            16  C1y C    12.5634  -21.0931
            17  O7x O    13.3514  -22.2462
            18  C7x C    14.6895  -21.8347
            19  O6a O    15.7753  -22.7458
            20  C1b C    11.1300  -21.0728
            21  N1b N    10.4461  -19.8484
            22  C5a C     9.0310  -19.8980
            23  C1a C     8.2805  -18.6975
            24  O5a O     8.3810  -21.1205
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    7  12 1
            14    3  13 1
            15    5  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   14  18 1
            21   18  19 2
            22   16  20 1 #Up
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   22  24 2

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