KEGG   DRUG: Homatropine hydrobromideHelp
Entry
D01004                      Drug                                   

Name
Homatropine hydrobromide (JP17/USP);
Isopto homatropine (TN)
Product
  Other
Formula
C16H21NO3. HBr
Exact mass
355.0783
Mol weight
356.2548
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Remark
ATC code: S01FA05
Chemical structure group: DG01142
Product (DG01142): D01004<US>
Efficacy
Mydriatic, Muscarinic acetylcholine receptor antagonist
Comment
Tropane derivative
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
Interaction
Drug interaction
Structure map
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA05 Homatropine
      D01004  Homatropine hydrobromide (JP17/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Homatropine
      D01004  Homatropine hydrobromide (JP17/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01004  Homatropine hydrobromide
BRITE hierarchy
Other DBs
CAS: 51-56-9
PubChem: 7848067
ChEMBL: CHEMBL1319362
LigandBox: D01004
NIKKAJI: J237.403J
KCF data Show

ATOM        21
            1   X   Br   35.9441  -16.6432
            2   C1x C    26.0638  -19.5108
            3   C1x C    26.3919  -18.3391
            4   C1y C    27.2355  -19.2296
            5   C1y C    27.5636  -18.0579
            6   N1y N    26.2982  -16.7456
            7   C1x C    29.1102  -19.2296
            8   C1x C    28.8290  -18.0579
            9   C1y C    30.1413  -19.7920
            10  O7a O    31.2193  -20.6825
            11  C7a C    32.4379  -20.6825
            12  C1c C    33.0472  -19.6045
            13  O6a O    33.0472  -21.8073
            14  C8y C    34.2658  -19.6045
            15  O1a O    32.4379  -18.5734
            16  C8x C    34.9720  -20.8282
            17  C8x C    36.3720  -20.8285
            18  C8x C    37.0722  -19.6162
            19  C8x C    36.3661  -18.3925
            20  C8x C    34.9661  -18.3922
            21  C1a C    25.5491  -15.5614
BOND        22
            1     2   3 1
            2     2   4 1
            3     3   5 1
            4     4   6 1
            5     4   7 1
            6     5   8 1
            7     7   9 1
            8     9  10 1 #Down
            9    10  11 1
            10   11  12 1
            11   11  13 2
            12   12  14 1
            13   12  15 1
            14    5   6 1
            15    8   9 1
            16   14  16 2
            17   16  17 1
            18   17  18 2
            19   18  19 1
            20   19  20 2
            21   14  20 1
            22    6  21 1

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