KEGG   DRUG: D01006Help
Entry
D01006                      Drug                                   

Name
Oxyphencyclimine hydrochloride (JAN);
Daricon (TN)
Formula
C20H28N2O3. HCl
Exact mass
380.1867
Mol weight
380.9089
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticholinergics
Remark
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor M3 antagonist [HSA:1131] [KO:K04131]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AA Synthetic anticholinergics, esters with tertiary amino group
     A03AA01 Oxyphencyclimine
      D01006  Oxyphencyclimine hydrochloride (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Oxyphencyclimine
    D01006  Oxyphencyclimine hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor M3
     Oxyphencyclimine
      D01006  Oxyphencyclimine hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
125-52-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   X   Cl   20.5800  -20.4400
            2   C1x C     8.0500  -17.3600
            3   C1x C     8.0500  -18.7600
            4   N1y N     9.2624  -19.4600
            5   C2y C    10.4749  -18.7600
            6   N2x N    10.4749  -17.3600
            7   C1x C     9.2624  -16.6600
            8   C1b C    11.7124  -19.4600
            9   O7a O    12.9249  -18.7600
            10  C7a C    14.1373  -19.4600
            11  C1d C    15.3497  -18.7600
            12  C8y C    16.5622  -19.4600
            13  C1y C    15.3497  -17.3601
            14  C1x C    16.5473  -16.6686
            15  C1x C    16.5472  -15.2686
            16  C1x C    15.3347  -14.5687
            17  C1x C    14.1371  -15.2602
            18  C1x C    14.1372  -16.6602
            19  C8x C    16.5622  -20.8597
            20  C8x C    17.7746  -21.5597
            21  C8x C    18.9871  -20.8597
            22  C8x C    18.9870  -19.4600
            23  C8x C    17.7746  -18.7600
            24  O1a O    16.5622  -18.0600
            25  O6a O    14.1373  -20.8600
            26  C1a C     9.2624  -20.8598
BOND        27
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 2
            5     6   7 1
            6     2   7 1
            7     5   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   11  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   13  18 1
            19   12  19 2
            20   19  20 1
            21   20  21 2
            22   21  22 1
            23   22  23 2
            24   12  23 1
            25   11  24 1
            26   10  25 2
            27    4  26 1

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