KEGG   DRUG: D01007Help
Entry
D01007                      Drug                                   

Name
Propiverine hydrochloride (JP16);
Bup-4 (TN);
Mictonorm (TN)
Formula
C23H29NO3. HCl
Exact mass
403.1914
Mol weight
403.9422
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Parasympatholytic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BD Urinary antispasmodics
     G04BD06 Propiverine
      D01007  Propiverine hydrochloride (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  25  Urogenital and anal organ agents
   259  Miscellaneous
    2590  Miscellaneous
     D01007  Propiverine hydrochloride (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Propiverine
      D01007  Propiverine hydrochloride (JP16)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP3A4
   Propiverine
    D01007  Propiverine hydrochloride (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01007  Propiverine hydrochloride
  D01007  Propiverine hydrochloride tablets
BRITE hierarchy
Other DBs
CAS: 
54556-98-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   X   Cl   31.6971  -21.2255
            2   C1x C    19.9430  -20.7678
            3   N1y N    19.9430  -22.1663
            4   C1x C    21.1541  -22.8656
            5   C1x C    22.3654  -22.1663
            6   C1y C    22.3654  -20.7678
            7   C1x C    21.1541  -20.0686
            8   O7a O    23.6015  -20.0686
            9   C7a C    24.8128  -20.7678
            10  C1d C    26.0239  -20.0686
            11  C8y C    27.2350  -20.7678
            12  C8x C    28.4462  -20.0686
            13  C8x C    29.6573  -20.7678
            14  C8y C    26.0239  -18.6701
            15  C8x C    27.2371  -17.9696
            16  C8x C    27.2371  -16.5711
            17  C8x C    26.0259  -15.8718
            18  C8x C    24.8128  -16.5723
            19  C8x C    24.8128  -17.9708
            20  C8x C    27.2350  -22.1663
            21  C8x C    28.4462  -22.8656
            22  C8x C    29.6573  -22.1663
            23  O2a O    27.2350  -19.3693
            24  C1b C    28.4462  -18.6701
            25  C1b C    29.6780  -19.3815
            26  C1a C    30.8829  -18.6860
            27  O6a O    24.8128  -22.1661
            28  C1a C    18.7319  -22.8656
BOND        29
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     2   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 2
            13   10  14 1
            14   14  15 1
            15   15  16 2
            16   16  17 1
            17   17  18 2
            18   18  19 1
            19   14  19 2
            20   11  20 2
            21   20  21 1
            22   21  22 2
            23   22  13 1
            24   10  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28    9  27 2
            29    3  28 1

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