KEGG   DRUG: D01011Help
Entry
D01011                      Drug                                   

Name
Liothyronine sodium (JP17/USAN);
Cytomel (TN);
Triostat (TN)
Product
  Generic
LIOTHYRONINE SODIUM (Aidarex Pharmaceuticals LLC), LIOTHYRONINE SODIUM (Carilion Materials Management), LIOTHYRONINE SODIUM (Carilion Materials Management), LIOTHYRONINE SODIUM (Golden State Medical Supply), LIOTHYRONINE SODIUM (KAISER FOUNDATION HOSPITALS), LIOTHYRONINE SODIUM (KAISER FOUNDATION HOSPITALS), LIOTHYRONINE SODIUM (Lake Erie Medical DBA Quality Care Products LLC), LIOTHYRONINE SODIUM (Medsource Pharmaceuticals), LIOTHYRONINE SODIUM (Mylan Pharmaceuticals), LIOTHYRONINE SODIUM (Northwind Pharmaceuticals), LIOTHYRONINE SODIUM (Northwind Pharmaceuticals), LIOTHYRONINE SODIUM (PD-Rx Pharmaceuticals), LIOTHYRONINE SODIUM (PD-Rx Pharmaceuticals), LIOTHYRONINE SODIUM (Paddock Laboratories), LIOTHYRONINE SODIUM (SIGMAPHARM LABORATORIES), LIOTHYRONINE SODIUM (Stat Rx USA), LIOTHYRONINE SODIUM (X-GEN Pharmaceuticals)
Formula
C15H11I3NO4. Na
Exact mass
672.772
Mol weight
672.9553
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Thyroid hormone
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
thyroid hormone receptor, alpha agonist [HSA:7067] [KO:K05547];
thyroid hormone receptor, beta agonist [HSA:7068] [KO:K08362]
  Pathway
Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
Antineoplastics - hormones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H03 THYROID THERAPY
   H03A THYROID PREPARATIONS
    H03AA Thyroid hormones
     H03AA02 Liothyronine sodium
      D01011  Liothyronine sodium (JP17/USAN)
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Thyroid)
  Liothyronine
   D01011  Liothyronine sodium (JP16/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   243  Thyroid and parathyroid hormone preparations
    2431  Thyroid hormones
     D01011  Liothyronine sodium (JP17/USAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Thyroid hormone receptor (THR)
    thyroid hormone receptor, alpha
     Liothyronine sodium
      D01011  Liothyronine sodium (JP17/USAN)
    thyroid hormone receptor, beta
     Liothyronine sodium
      D01011  Liothyronine sodium (JP17/USAN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01011  Liothyronine sodium
  D01011  Liothyronine sodium tablets
Endocrine and hormonal agents [br08373.html]
 Hormone related agents
  D01011
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D01011
BRITE hierarchy
Other DBs
CAS: 
55-06-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8y C    22.6938  -17.3834
            2   O2a O    23.9120  -18.0919
            3   C8y C    21.4993  -18.0919
            4   C8y C    22.6938  -15.9897
            5   C8y C    25.1241  -18.7889
            6   C8x C    20.2754  -17.3834
            7   X   I    21.4993  -19.4857
            8   C8x C    21.4993  -15.2870
            9   X   I    23.9120  -15.2870
            10  C8x C    26.3421  -18.0919
            11  C8x C    25.1241  -20.1884
            12  C8y C    20.2754  -15.9897
            13  C8y C    27.5543  -18.7889
            14  C8x C    26.3421  -20.8911
            15  C1b C    19.0632  -15.2870
            16  C8y C    27.5543  -20.1884
            17  X   I    28.7605  -18.0919
            18  C1c C    17.8453  -15.9897
            19  O1a O    28.7605  -20.8911
            20  C6a C    16.6331  -15.2870
            21  N1a N    17.8453  -17.3834
            22  O6a O    16.6331  -13.8875
            23  O6a O    15.4149  -15.9897 #-
            24  Z   Na   13.6172  -13.9050 #+
BOND        24
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 2
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12   10  13 2
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   15  18 1
            18   16  19 1
            19   18  20 1
            20   18  21 1 #Down
            21   20  22 2
            22   20  23 1
            23    8  12 1
            24   14  16 2

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