KEGG   DRUG: D01019Help
Entry
D01019                      Drug                                   

Name
Metaraminol bitartrate (JAN/USP);
Aramine (TN)
Formula
C9H13NO2. C4H6O6
Exact mass
317.1111
Mol weight
317.2919
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Adrenergic
Remark
ATC code: 
Target
alpha1-adrenergic receptor agonist [HSA:146 147 148] [KO:K04137 K04136 K04135];
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA09 Metaraminol
      D01019  Metaraminol bitartrate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
     Metaraminol [ATC:C01CA09]
      D01019  Metaraminol bitartrate (JAN/USP)
    alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
     Metaraminol [ATC:C01CA09]
      D01019  Metaraminol bitartrate (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
33402-03-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    21.4906  -19.3607
            2   C8x C    20.2832  -18.6667
            3   C8x C    21.4906  -20.7665
            4   C1c C    22.7037  -18.6667
            5   C8y C    19.0642  -19.3607
            6   C8x C    20.2832  -21.4722
            7   C1c C    22.7037  -17.2611
            8   O1a O    23.9168  -19.3607
            9   C8x C    19.0642  -20.7665
            10  O1a O    17.8509  -18.6667
            11  C1a C    21.4906  -16.5553
            12  N1a N    23.9168  -16.5553
            13  C1c C    29.8719  -19.3374
            14  C1c C    31.0793  -18.6434
            15  C6a C    28.6588  -18.6491
            16  O1a O    29.8719  -20.7372
            17  C6a C    32.2925  -19.3316
            18  O1a O    31.0735  -17.2378
            19  O6a O    27.4514  -19.3433
            20  O6a O    28.6588  -17.2495
            21  O6a O    33.5057  -18.6317
            22  O6a O    32.2983  -20.7315
BOND        21
            1     1   2 2
            2     1   3 1
            3     4   1 1 #Down
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     4   8 1
            8     5   9 2
            9     5  10 1
            10    7  11 1
            11    7  12 1 #Down
            12    6   9 1
            13   13  14 1
            14   13  15 1
            15   13  16 1 #Up
            16   14  17 1
            17   14  18 1 #Up
            18   15  19 1
            19   15  20 2
            20   17  21 1
            21   17  22 2

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