KEGG   DRUG: Metaraminol bitartrateHelp
Entry
D01019                      Drug                                   

Name
Metaraminol bitartrate (JAN/USP);
Aramine (TN)
Formula
C9H13NO2. C4H6O6
Exact mass
317.1111
Mol weight
317.2919
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
Remark
ATC code: 
Chemical group: 
Activity
Antihypotensive, alpha-Adrenergic receptor agonist
Comment
Phenethylamine derivative
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137];
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Salivary secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA09 Metaraminol
      D01019  Metaraminol bitartrate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Metaraminol
      D01019  Metaraminol bitartrate (JAN/USP)
    alpha2-adrenergic receptor
     Metaraminol
      D01019  Metaraminol bitartrate (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
33402-03-8
PubChem: 
ChEBI: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1c C    22.8019  -16.4674
            2   C1c C    24.0093  -15.7734
            3   C6a C    21.5888  -15.7791
            4   O1a O    22.8019  -17.8672
            5   C6a C    25.2225  -16.4616
            6   O1a O    24.0035  -14.3678
            7   O6a O    20.3814  -16.4733
            8   O6a O    21.5888  -14.3795
            9   O6a O    26.4357  -15.7617
            10  O6a O    25.2283  -17.8615
            11  C8y C    10.5700  -16.4500
            12  C8x C    10.5700  -17.8500
            13  C8x C    11.7600  -18.5500
            14  C8x C    13.0200  -17.8500
            15  C8y C    13.0200  -16.4500
            16  C8x C    11.7600  -15.7500
            17  O1a O     9.3800  -15.7500
            18  C1c C    14.2100  -15.7500
            19  C1c C    15.4700  -16.4500
            20  O1a O    14.2100  -14.3500
            21  N1a N    16.6600  -15.7500
            22  C1a C    15.4700  -17.8500
BOND        21
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 2
            8     5   9 1
            9     5  10 2
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13   14  15 1
            14   15  16 2
            15   11  16 1
            16   11  17 1
            17   15  18 1
            18   18  19 1
            19   18  20 1 #Up
            20   19  21 1 #Up
            21   19  22 1

» Japanese version   » Back

DBGET integrated database retrieval system