KEGG   DRUG: Methoxamine hydrochlorideHelp
Entry
D01020                      Drug                                   

Name
Methoxamine hydrochloride (JAN);
Vasoxyl (TN)
Formula
C11H17NO3. HCl
Exact mass
247.0975
Mol weight
247.7185
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
    DG01654  alpha1-Adrenergic receptor specific agonist
Remark
ATC code: 
Chemical group: 
Efficacy
Antihypotensive, alpha1-Adrenergic receptor agonist
Comment
Phenethylamine derivative
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Salivary secretion
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA10 Methoxamine
      D01020  Methoxamine hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Methoxamine
      D01020  Methoxamine hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
61-16-5
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        16
            1   X   Cl   23.5422  -17.9534
            2   C8y C    14.5600  -16.5200
            3   C8x C    14.5600  -17.9200
            4   C8x C    15.7500  -18.6200
            5   C8y C    17.0100  -17.9200
            6   C8y C    17.0100  -16.5200
            7   C8x C    15.7500  -15.8200
            8   C1c C    18.2000  -15.8200
            9   C1c C    19.3900  -16.5200
            10  O1a O    18.2000  -14.4200
            11  N1a N    20.5800  -15.8200
            12  C1a C    19.3900  -17.9200
            13  O2a O    13.3700  -15.8200
            14  C1a C    12.1800  -16.5200
            15  O2a O    18.2000  -18.6200
            16  C1a C    18.2000  -20.0200
BOND        15
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     6   8 1
            8     8   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 1
            12    2  13 1
            13   13  14 1
            14    5  15 1
            15   15  16 1

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