| Entry |
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| Name |
Naphazoline nitrate (JP16);
Privine (TN)
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| Formula |
C14H14N2. HNO3
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| Exact mass |
273.1113
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| Mol weight |
273.2872
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| Structure |
     |
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| Activity |
Adrenergic [vasoconstrictor]
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| Remark |
Therapeutic category: ATC code: |
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
| Naphthalene family | | alpha-Adrenergic receptor agonists/antagonists |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1316 Ophthalmic local vasoconstrictors
D01021 Naphazoline nitrate (JP16)
132 Otic and nasal agents
1324 Otolaryngologic vasoconstrictors
D01021 Naphazoline nitrate (JP16)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA08 Naphazoline
D01021 Naphazoline nitrate (JP16)
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB02 Naphazoline
D01021 Naphazoline nitrate (JP16)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA01 Naphazoline
D01021 Naphazoline nitrate (JP16)
USP drug classification [BR:br08302]
Ophthalmic Agents
Ophthalmic Agents, Other
Naphazoline
D01021 Naphazoline nitrate (JP16)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
Naphazoline [ATC:R01AA08 R01AB02 S01GA01]
D01021 Naphazoline nitrate (JP16)
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| Other DBs |
CAS: 5144-52-5 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 20
1 N2b N 36.3244 -19.0105 #+
2 O3a O 36.3186 -17.6140
3 O3a O 37.5567 -19.7146 #-
4 O1b O 35.1065 -19.7205
5 C8y C 28.2800 -18.6900
6 C8y C 29.4700 -17.9900
7 C8y C 28.2800 -20.0900
8 C8x C 27.0900 -17.9900
9 C1b C 29.4700 -16.5900
10 C8x C 30.8000 -18.6900
11 C8x C 29.4700 -20.7900
12 C8x C 27.0900 -20.7900
13 C8x C 25.8300 -18.6900
14 C2y C 30.7300 -15.8900
15 C8x C 30.8000 -20.0900
16 C8x C 25.8300 -20.0900
17 N1x N 32.0600 -16.3800
18 N2x N 30.7300 -14.5600
19 C1x C 32.9000 -15.1900
20 C1x C 32.0600 -14.0700
BOND 21
1 1 2 2
2 1 3 1
3 1 4 1
4 5 6 1
5 5 7 2
6 5 8 1
7 6 9 1
8 6 10 2
9 7 11 1
10 7 12 1
11 8 13 2
12 9 14 1
13 10 15 1
14 12 16 2
15 14 17 1
16 14 18 2
17 17 19 1
18 18 20 1
19 11 15 2
20 13 16 1
21 19 20 1
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