KEGG   DRUG: D01073Help
Entry
D01073                      Drug                                   

Name
Clindamycin phosphate (JP16/USP);
Cleocin (TN);
Dalacin-S (TN);
Evoclin (TN)
Product
  Generic
CLINDAMYCIN (General Injectables & Vaccines), CLINDAMYCIN (APP Pharmaceuticals), CLINDAMYCIN (APP Pharmaceuticals), CLINDAMYCIN (Akorn), CLINDAMYCIN (Cardinal Health), CLINDAMYCIN (Cardinal Health), CLINDAMYCIN PHOSPHATE (E. FOUGERA & CO. A division of Fougera Pharmaceuticals), CLINDAMYCIN PHOSPHATE (E. Fougera & Co. a division of Fougera Pharmaceuticals), CLINDAMYCIN PHOSPHATE (Greenstone LLC), CLINDAMYCIN PHOSPHATE (Greenstone LLC), CLINDAMYCIN (Hospira), CLINDAMYCIN (Hospira), CLINDAMYCIN (Hospira), CLINDAMYCIN PHOSPHATE (Lake Erie Medical DBA Quality Care Products LLC), CLINDAMYCIN PHOSPHATE (Medimetriks Pharmaceuticals), CLINDACIN ETZ (Medimetriks Pharmaceuticals), CLINDAMAX (PHARMADERM. A division of Nycomed US), CLINDA-DERM (Paddock Laboratoratories), CLINDAMYCIN PHOSPHATE (Perrigo New York), CLINDAMYCIN PHOSPHATE (Perrigo New York), CLINDAMYCIN PHOSPHATE (Perrigo New York), CLINDAMAX (PharmaDerm), CLINDAMAX LOTION (PharmaDerm), CLINDAMYCIN PHOSPHATE (Physicians Total Care), CLINDAMYCIN PHOSPHATE (Physicians Total Care), CLINDAMYCIN PHOSPHATE (Physicians Total Care), CLINDAMYCIN PHOSPHATE (Physicians Total Care), CLINDAMYCIN PHOSPHATE (Preferred Pharmaceuticals), CLINDAMYCIN PHOSPHATE (Preferred Pharmaceuticals), CLINDAMYCIN PHOSPHATE (Rebel Distributors Corp), CLINDAMYCIN (Sagent Pharmaceuticals), CLINDAMYCIN (Sagent Pharmaceuticals), CLINDAMYCIN PHOSPHATE (Taro Pharmaceuticals U.S.A.), CLINDAMYCIN PHOSPHATE (VersaPharm Incorporated)
Formula
C18H34ClN2O8PS
Exact mass
504.1462
Mol weight
504.9629
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic lincosamide
prodrug, active substance: Clindamycin [DR:D00277]
Target
23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor [KO:K01980]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AF Antiinfectives for treatment of acne
     D10AF01 Clindamycin
      D01073  Clindamycin phosphate (JP16/USP)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA10 Clindamycin
      D01073  Clindamycin phosphate (JP16/USP)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FF Lincosamides
     J01FF01 Clindamycin
      D01073  Clindamycin phosphate (JP16/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Clindamycin
    D01073  Clindamycin phosphate (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2634  Antibiotics for external use
     D01073  Clindamycin phosphate (JP16/USP)
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   611  Acting mainly on gram-positive bacteria
    6112  Lincomycins
     D01073  Clindamycin phosphate (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   23S rRNA of 50S ribosomal subunit inhibitor
    Lincosamides
     Clindamycin
      D01073  Clindamycin phosphate (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01073  Clindamycin phosphate
  D01073  Clindamycin phosphate injection
BRITE hierarchy
Other DBs
CAS: 
24729-96-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C1y C    20.3420  -15.6751
            2   C1y C    20.3420  -17.0766
            3   C1y C    21.5567  -17.7773
            4   C1y C    22.7713  -17.0766
            5   C1y C    22.7713  -15.6751
            6   O2x O    21.5567  -14.9744
            7   S2a S    23.9859  -14.9744
            8   C1a C    23.9859  -13.5730
            9   O2b O    23.9859  -17.7773
            10  O1a O    21.5567  -19.1789
            11  O1a O    19.1275  -17.7773
            12  C1c C    19.1275  -14.9744
            13  N1b N    17.9129  -15.6751
            14  C1c C    19.1275  -13.5730
            15  X   Cl   17.9129  -12.8722
            16  C1a C    20.3420  -12.8722
            17  C5a C    16.6983  -14.9744
            18  C1y C    15.4837  -15.6751
            19  O5a O    16.6983  -13.5730
            20  N1y N    14.3578  -14.8803
            21  C1x C    13.2387  -15.7030
            22  C1y C    13.6855  -17.0322
            23  C1x C    15.0690  -17.0253
            24  C1a C    14.3578  -13.4808
            25  C1b C    12.9918  -18.2479
            26  C1b C    11.6141  -18.2550
            27  C1a C    10.9162  -19.4785
            28  P1b P    25.2093  -17.0704
            29  O1c O    26.4215  -16.3706
            30  O1c O    24.5068  -15.8540
            31  O1c O    25.9066  -18.2777
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     7   8 1
            9     4   9 1 #Down
            10    3  10 1 #Up
            11    2  11 1 #Up
            12    1  12 1
            13   12  13 1
            14   12  14 1
            15   14  15 1 #Up
            16   14  16 1
            17   13  17 1
            18   18  17 1 #Down
            19   17  19 2
            20   18  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   18  23 1
            25   20  24 1
            26   22  25 1 #Up
            27   25  26 1
            28   26  27 1
            29    9  28 1
            30   28  29 1
            31   28  30 2
            32   28  31 1

» Japanese version   » Back

DBGET integrated database retrieval system