KEGG   DRUG: Methylatropine nitrateHelp
Entry
D01077                      Drug                                   

Name
Methylatropine nitrate (USAN);
Atropine methonitrate (JAN/INN);
Ekomine (TN)
Formula
C18H26NO3. NO3
Exact mass
366.1791
Mol weight
366.4088
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Remark
ATC code: 
Chemical group: 
Activity
Antispasmodic, Anticholinergic
Comment
Tropane derivative, Quaternary ammonium compound
Target
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BB Belladonna alkaloids, semisynthetic, quaternary ammonium compounds
     A03BB02 Methylatropine
      D01077  Methylatropine nitrate (USAN)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Atropine
    D01077  Methylatropine nitrate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Methylatropine
      D01077  Methylatropine nitrate (USAN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D01077  Atropine methonitrate (JAN/INN); Methylatropine nitrate (USAN)
BRITE hierarchy
Other DBs
CAS: 
52-88-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   N2b N    32.1276  -18.8381 #+
            2   O3a O    32.1276  -17.7275
            3   O3a O    30.8418  -19.6973 #-
            4   O3a O    33.4778  -19.5804 #-
            5   C1x C    18.2238  -19.1608
            6   C1x C    18.5519  -17.9891
            7   C1y C    19.3955  -18.8796
            8   C1y C    19.7236  -17.7079
            9   N2y N    18.4582  -16.3956 #+
            10  C1x C    21.2702  -18.8796
            11  C1x C    20.9890  -17.7079
            12  C1y C    22.3013  -19.4420
            13  O7a O    23.3793  -20.3325
            14  C7a C    24.5979  -20.3325
            15  C1c C    25.2072  -19.2545
            16  O6a O    25.2072  -21.4573
            17  C8y C    26.4258  -19.2545
            18  C1b C    24.5979  -18.2234
            19  O1a O    25.2072  -17.1455
            20  C8x C    27.1320  -20.4782
            21  C8x C    28.5320  -20.4785
            22  C8x C    29.2322  -19.2662
            23  C8x C    28.5261  -18.0425
            24  C8x C    27.1261  -18.0422
            25  C1a C    17.7091  -15.2114
            26  C1a C    17.2289  -17.0083
BOND        27
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     5   6 1
            5     5   7 1
            6     6   8 1
            7     7   9 1
            8     7  10 1
            9     8  11 1
            10   10  12 1
            11   12  13 1 #Down
            12   13  14 1
            13   14  15 1
            14   14  16 2
            15   15  17 1
            16   15  18 1
            17   18  19 1
            18    8   9 1
            19   11  12 1
            20   17  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   17  24 1
            26    9  25 1
            27    9  26 1

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