KEGG   DRUG: D01097Help
Entry
D01097                      Drug                                   

Name
Lazabemide hydrochloride (JAN/USAN);
Tempium (TN)
Formula
C8H10ClN3O. HCl
Exact mass
235.0279
Mol weight
236.0984
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian;
Treatment of Alzheimer's disease
Remark
Drug group: 
Target
monoamine oxidase B (MAO-B) inhibitor [HSA:4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Structure map
Catecholamine transferase inhibitors
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase B (MAO-B)
    Lazabemide
     D01097  Lazabemide hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
103878-83-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8x C    20.4784  -19.0125
            2   C8y C    20.4784  -20.4136
            3   C8x C    21.6947  -21.1142
            4   C8x C    22.9039  -20.4136
            5   C8y C    22.9039  -19.0125
            6   N5x N    21.6947  -18.3120
            7   C5a C    24.1179  -18.3128
            8   N1b N    25.3308  -19.0142
            9   O5a O    24.1189  -16.9117
            10  C1b C    26.5358  -18.3120
            11  C1b C    27.7458  -19.0125
            12  N1a N    28.9559  -18.3120
            13  X   Cl   19.2654  -21.1147
            14  X   Cl   32.6900  -18.3400
BOND        13
            1     5   7 1
            2     7   8 1
            3     1   2 2
            4     7   9 2
            5     2   3 1
            6     8  10 1
            7     3   4 2
            8    10  11 1
            9     4   5 1
            10   11  12 1
            11    5   6 2
            12    2  13 1
            13    6   1 1

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