KEGG   DRUG: D01105Help
Entry
D01105                      Drug                                   

Name
Moperone hydrochloride (JAN);
Luvatren (TN)
Formula
C22H26FNO2. HCl
Exact mass
391.1714
Mol weight
391.9067
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antipsychotic
Remark
ATC code: 
Drug group: 
Comment
Butyrophenone derivatives
Target
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Butyrophenones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AD Butyrophenone derivatives
     N05AD04 Moperone
      D01105  Moperone hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Moperone
      D01105  Moperone hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
3871-82-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   X   Cl   34.2300  -16.3100
            2   C1b C    18.0600  -17.5700
            3   C1b C    19.3200  -16.8700
            4   C1b C    20.5100  -17.5700
            5   N1y N    21.7000  -16.8700
            6   C1x C    21.7000  -15.4700
            7   C1x C    22.8900  -17.5700
            8   C1x C    22.8900  -14.7700
            9   C1x C    24.0800  -16.8700
            10  C1z C    24.0800  -15.4700
            11  C8y C    25.2700  -14.7700
            12  C8x C    25.2700  -13.3700
            13  C8x C    26.4600  -15.4700
            14  C8x C    26.4600  -12.7400
            15  C8x C    27.6500  -14.7700
            16  C8y C    27.6500  -13.4400
            17  C1a C    28.8400  -12.7400
            18  C5a C    16.8700  -16.8000
            19  C8y C    15.6100  -17.5700
            20  O5a O    16.8700  -15.4000
            21  C8x C    15.6100  -18.9700
            22  C8x C    14.4200  -19.6700
            23  C8y C    13.1600  -18.9700
            24  C8x C    13.1600  -17.5700
            25  C8x C    14.4200  -16.8000
            26  X   F    11.9700  -19.6700
            27  O1a O    25.2924  -16.1700
BOND        28
            1    10  11 1
            2    11  12 1
            3    11  13 2
            4    12  14 2
            5    13  15 1
            6    14  16 1
            7    16  17 1
            8     9  10 1
            9    15  16 2
            10    2  18 1
            11    2   3 1
            12   18  19 1
            13    3   4 1
            14   18  20 2
            15    4   5 1
            16    5   6 1
            17    5   7 1
            18    6   8 1
            19    7   9 1
            20   19  21 1
            21   21  22 2
            22   22  23 1
            23   23  24 2
            24   24  25 1
            25   25  19 2
            26    8  10 1
            27   23  26 1
            28   10  27 1

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