| Entry |
|
|---|
| Name |
Moperone hydrochloride (JAN);
Luvatren (TN) |
|---|
| Formula |
C22H26FNO2. HCl
|
|---|
| Exact mass |
391.1714
|
|---|
| Mol weight |
391.9067
|
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| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Butyrophenone derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07031 | Antipsychotics - butyrophenones |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD04 Moperone
D01105 Moperone hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00888 Moperone
D01105 Moperone hydrochloride
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00888 Moperone
D01105 Moperone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D01105 Moperone hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00888 Moperone
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
DG00888 Moperone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 27
1 X Cl 34.2300 -16.3100
2 C1b C 18.0600 -17.5700
3 C1b C 19.3200 -16.8700
4 C1b C 20.5100 -17.5700
5 N1y N 21.7000 -16.8700
6 C1x C 21.7000 -15.4700
7 C1x C 22.8900 -17.5700
8 C1x C 22.8900 -14.7700
9 C1x C 24.0800 -16.8700
10 C1z C 24.0800 -15.4700
11 C8y C 25.2700 -14.7700
12 C8x C 25.2700 -13.3700
13 C8x C 26.4600 -15.4700
14 C8x C 26.4600 -12.7400
15 C8x C 27.6500 -14.7700
16 C8y C 27.6500 -13.4400
17 C1a C 28.8400 -12.7400
18 C5a C 16.8700 -16.8000
19 C8y C 15.6100 -17.5700
20 O5a O 16.8700 -15.4000
21 C8x C 15.6100 -18.9700
22 C8x C 14.4200 -19.6700
23 C8y C 13.1600 -18.9700
24 C8x C 13.1600 -17.5700
25 C8x C 14.4200 -16.8000
26 X F 11.9700 -19.6700
27 O1a O 25.2924 -16.1700
BOND 28
1 10 11 1
2 11 12 1
3 11 13 2
4 12 14 2
5 13 15 1
6 14 16 1
7 16 17 1
8 9 10 1
9 15 16 2
10 2 18 1
11 2 3 1
12 18 19 1
13 3 4 1
14 18 20 2
15 4 5 1
16 5 6 1
17 5 7 1
18 6 8 1
19 7 9 1
20 19 21 1
21 21 22 2
22 22 23 1
23 23 24 2
24 24 25 1
25 25 19 2
26 8 10 1
27 23 26 1
28 10 27 1
|
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