KEGG   DRUG: D01117Help
Entry
D01117                      Drug                                   

Name
Mizolastine (JAN/INN);
Mizollen (TN)
Formula
C24H25FN6O
Exact mass
432.2074
Mol weight
432.4933
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
antihistaminics
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX25 Mizolastine
      D01117  Mizolastine (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Mizolastine
      D01117  Mizolastine (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
108612-45-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C1b C    22.1907  -15.3549
            2   C8y C    20.9802  -14.6492
            3   C8x C    20.9897  -13.2479
            4   C8x C    19.7791  -12.5420
            5   C8y C    18.5626  -13.2375
            6   C8x C    18.5567  -14.6388
            7   C8x C    19.7673  -15.3445
            8   X   F    17.3521  -12.5316
            9   N4y N    22.1800  -16.7509
            10  C8x C    18.4164  -17.1795
            11  C8x C    18.4164  -18.5808
            12  C8x C    19.6329  -19.2814
            13  C8x C    19.6329  -16.4788
            14  C8y C    20.8423  -17.1795
            15  C8y C    20.8365  -18.5842
            16  N5x N    22.1707  -19.0239
            17  C8y C    23.0008  -17.8908
            18  N1y N    24.3966  -17.8873
            19  C1x C    25.0978  -19.0944
            20  C1x C    26.4936  -19.0909
            21  C1y C    27.1885  -17.8801
            22  C1x C    26.4875  -16.6731
            23  C1x C    25.0915  -16.6767
            24  N1c N    28.5898  -17.8766
            25  C8y C    29.2935  -19.0883
            26  C1a C    29.2874  -16.6613
            27  N5x N    28.5925  -20.2955
            28  C8x C    29.2962  -21.5072
            29  C8x C    30.6975  -21.5036
            30  C8y C    31.3951  -20.2882
            31  N4x N    30.6914  -19.0764
            32  O5x O    32.7964  -20.2846
BOND        36
            1    11  12 2
            2    12  15 1
            3    14  13 1
            4    14  15 2
            5    15  16 1
            6    17  18 1
            7     1   9 1
            8     2   3 2
            9     3   4 1
            10    4   5 2
            11    5   6 1
            12   18  19 1
            13   19  20 1
            14   20  21 1
            15   21  22 1
            16   22  23 1
            17   23  18 1
            18    6   7 2
            19   21  24 1
            20    7   2 1
            21   24  25 1
            22    1   2 1
            23   24  26 1
            24    5   8 1
            25   16  17 2
            26   17   9 1
            27    9  14 1
            28   13  10 2
            29   25  27 2
            30   27  28 1
            31   28  29 2
            32   29  30 1
            33   30  31 1
            34   31  25 1
            35   10  11 1
            36   30  32 2

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