KEGG   DRUG: D01131Help
Entry
D01131                      Drug                                   

Name
Lafutidine (JP16/INN);
Protecadin (TN)
Formula
C22H29N3O4S
Exact mass
431.1879
Mol weight
431.5484
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
ATC code: 
Target
H2-receptor antagonist [HSA:3274] [KO:K04150]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiulcer drugs
Histamine H2/H3 receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   232  Peptic ulcer agents
    2325  H2 blockers
     D01131  Lafutidine (JP16/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A02 DRUGS FOR ACID RELATED DISORDERS
   A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
    A02BA H2-receptor antagonists
     A02BA08 Lafutidine
      D01131  Lafutidine (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H2-receptor [HSA:3274] [KO:K04150]
     Lafutidine [ATC:A02BA08]
      D01131  Lafutidine (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
118288-08-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C1x C    11.2700  -29.7500
            2   C1x C    11.2700  -31.1500
            3   C1x C    12.4600  -31.8500
            4   N1y N    13.7200  -31.1500
            5   C1x C    13.7200  -29.7500
            6   C1x C    12.4600  -29.0500
            7   C1b C    14.9100  -31.8500
            8   C8y C    16.1000  -31.1500
            9   C8x C    17.2900  -31.8500
            10  C8y C    18.5500  -31.1500
            11  N5x N    18.5500  -29.7500
            12  C8x C    17.3600  -29.0500
            13  C8x C    16.1000  -29.7500
            14  O2a O    19.7400  -31.8500
            15  C1b C    20.9300  -31.1500
            16  C2b C    22.1200  -31.8500
            17  C2b C    23.5200  -31.8500
            18  C1b C    24.7100  -31.1500
            19  N1b N    25.9000  -31.8500
            20  C5a C    27.0900  -31.1500
            21  C1b C    28.2800  -31.8500
            22  S4a S    29.4700  -31.1500
            23  C1b C    30.6600  -31.8500
            24  C8y C    31.8500  -31.1500
            25  O3c O    29.4700  -29.7500
            26  O5a O    27.0900  -29.7500
            27  C8x C    32.2700  -29.8200
            28  O2x O    32.9700  -31.9900
            29  C8x C    34.0900  -31.1500
            30  C8x C    33.6700  -29.8200
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15   10  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 2
            19   18  19 1
            20   18  17 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   22  25 2
            27   20  26 2
            28   27  24 2
            29   24  28 1
            30   28  29 1
            31   29  30 2
            32   27  30 1

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