KEGG   DRUG: PrulifloxacinHelp
Entry
D01144                      Drug                                   

Name
Prulifloxacin (JAN/INN);
PUFX;
Sword (TN)
Formula
C21H20FN3O6S
Exact mass
461.1057
Mol weight
461.4634
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Therapeutic category: 
ATC code: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Active form of prodrug: Ulifloxacin [CPD:C14492]
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA17 Prulifloxacin
      D01144  Prulifloxacin (JAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6241  Pyridonecarboxylic acids
     D01144  Prulifloxacin (JAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Prulifloxacin
      D01144  Prulifloxacin (JAN/INN)
Antibacterials [br08350.html]
 D01144
BRITE hierarchy
Other DBs
CAS: 
123447-62-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C8y C    26.6700  -19.5300
            2   C8y C    27.8600  -20.2300
            3   C8y C    25.4100  -20.2300
            4   C8y C    25.4100  -21.6300
            5   C8x C    24.2200  -22.4000
            6   C8y C    23.0300  -21.6300
            7   C8y C    23.0300  -20.2300
            8   C8x C    24.2200  -19.5300
            9   N1y N    21.7700  -22.4000
            10  C1x C    21.7700  -23.8000
            11  C1x C    20.5800  -24.5000
            12  C1x C    20.5800  -21.6300
            13  C1x C    19.3900  -22.4000
            14  N1y N    19.3900  -23.7300
            15  C1b C    18.1300  -24.4300
            16  C8y C    16.9400  -23.8000
            17  X   F    21.7700  -19.5300
            18  O5x O    26.6700  -18.1300
            19  N4y N    26.6700  -22.4000
            20  C8y C    27.8600  -21.6300
            21  S2x S    28.5600  -22.8900
            22  C1y C    27.3700  -23.5900
            23  C6a C    29.0500  -19.5300
            24  O6a O    29.0500  -18.1300
            25  O6a O    30.3100  -20.3000
            26  C1a C    27.0187  -24.9452
            27  O7x O    16.7427  -22.4140
            28  C8y C    15.3635  -22.1733
            29  O7x O    14.7084  -23.4106
            30  C8y C    15.6828  -24.4160
            31  O6a O    14.7478  -20.9168
            32  C1a C    15.4397  -25.8092
BOND        36
            1     5   6 2
            2    13  14 1
            3    14  15 1
            4    15  16 1
            5     6   7 1
            6     7   8 2
            7     8   3 1
            8     3   1 1
            9     6   9 1
            10    1   2 1
            11    2  20 2
            12    7  17 1
            13   19   4 1
            14    1  18 2
            15    9  10 1
            16   10  11 1
            17   11  14 1
            18   13  12 1
            19   19  20 1
            20   20  21 1
            21   21  22 1
            22   22  19 1
            23   12   9 1
            24    2  23 1
            25    3   4 2
            26   23  24 2
            27    4   5 1
            28   23  25 1
            29   22  26 1 #Down
            30   16  27 1
            31   27  28 1
            32   28  29 1
            33   29  30 1
            34   16  30 2
            35   28  31 2
            36   30  32 1

» Japanese version   » Back

DBGET integrated database retrieval system