KEGG   DRUG: PazufloxacinHelp
Entry
D01153                      Drug                                   

Name
Pazufloxacin (JAN/INN);
PZFX
Formula
C16H15FN2O4
Exact mass
318.1016
Mol weight
318.2997
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA18 Pazufloxacin
      D01153  Pazufloxacin (JAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Pazufloxacin
      D01153  Pazufloxacin (JAN/INN)
BRITE hierarchy
Other DBs
CAS: 
127045-41-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C1x C    20.3263  -21.4450
            2   C1z C    21.0246  -20.1880
            3   C1x C    21.7229  -21.4450
            4   C8y C    22.2117  -19.4898
            5   N1a N    19.8375  -19.4898
            6   O2x O    23.3988  -21.6544
            7   C1y C    25.7730  -21.6544
            8   C1x C    24.5859  -22.3527
            9   C8y C    23.3988  -20.2579
            10  C8y C    22.2117  -18.0932
            11  C8x C    23.3988  -17.3949
            12  N4y N    25.7730  -20.2579
            13  C8y C    24.5859  -19.5596
            14  C8y C    24.5859  -18.1630
            15  C8y C    25.7730  -17.4647
            16  C8y C    27.0299  -18.1630
            17  C8x C    27.0299  -19.5596
            18  C6a C    28.2170  -17.4647
            19  O6a O    28.2170  -16.0681
            20  O6a O    29.4041  -18.1630
            21  O5x O    25.7730  -16.0681
            22  X   F    20.9548  -17.3949
            23  C1a C    27.0299  -22.3527
BOND        26
            1     4  10 1
            2    10  11 2
            3    11  14 1
            4     1   3 1
            5     3   2 1
            6     6   9 1
            7    12   7 1
            8     7   8 1
            9    12  13 1
            10   13  14 2
            11   14  15 1
            12   15  16 1
            13   16  17 2
            14   17  12 1
            15    8   6 1
            16   16  18 1
            17    4   2 1
            18   18  19 2
            19    1   2 1
            20   18  20 1
            21    2   5 1
            22   15  21 2
            23   13   9 1
            24   10  22 1
            25    9   4 2
            26    7  23 1 #Up

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