KEGG   DRUG: D01157Help
Entry
D01157                      Drug                                   

Name
Cefepime dihydrochloride hydrate (JP16);
Cefepime hydrochloride (USP);
CFPM;
Maxipime (TN)
Product
  Generic
Formula
C19H25N6O5S2. HCl. Cl. H2O
Exact mass
570.0889
Mol weight
571.4982
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: broad spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DE Fourth-generation cephalosporins
     J01DE01 Cefepime
      D01157  Cefepime dihydrochloride hydrate (JP16); Cefepime hydrochloride (USP)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefepime
    D01157  Cefepime dihydrochloride hydrate (JP16); Cefepime hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6132  Cephem antibioitics
     D01157  Cefepime dihydrochloride hydrate (JP16); Cefepime hydrochloride (USP)
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   729  Miscellaneous
    7290  Miscellaneous
     D01157  Cefepime dihydrochloride hydrate (JP16); Cefepime hydrochloride (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefepime
      D01157  Cefepime dihydrochloride hydrate (JP16); Cefepime hydrochloride (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01157  Cefepime dihydrochloride hydrate
  D01157  Cefepime dihydrochloride for injection
BRITE hierarchy
Other DBs
CAS: 
123171-59-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        35
            1   X   Cl   19.3672  -22.6156
            2   X   Cl   29.6799  -18.2084 #-
            3   O0  O    22.4824  -22.5456
            4   C1y C    26.0672  -18.8627
            5   N1y N    26.0672  -20.2534
            6   C2y C    27.2717  -20.9487
            7   C2y C    28.4761  -20.2534
            8   C1x C    28.4761  -18.8627
            9   S2x S    27.2717  -18.1673
            10  C1y C    24.6764  -18.8627
            11  C5x C    24.6764  -20.2534
            12  N1b N    23.4722  -18.1673
            13  C5a C    22.2677  -18.8627
            14  O5a O    22.2677  -20.2534
            15  O5x O    23.4722  -20.9487
            16  C2c C    21.0633  -18.1673
            17  C1b C    29.6990  -20.9598
            18  C8y C    19.8396  -18.8743
            19  N2y N    30.9084  -20.2618 #+
            20  C8x C    18.7080  -18.0429
            21  S2x S    17.5629  -18.8608
            22  C8y C    17.9869  -20.2027
            23  N5x N    19.3940  -20.2140
            24  N2b N    21.0632  -16.7553
            25  C6a C    27.2717  -22.3560
            26  O6a O    28.4867  -23.0575
            27  O6a O    26.0583  -23.0567
            28  C1x C    30.9086  -18.8509
            29  C1x C    32.2501  -20.6980
            30  C1x C    33.0795  -19.5567
            31  C1x C    32.2504  -18.4151
            32  C1a C    30.9084  -21.6640
            33  N1a N    17.1436  -21.3437
            34  O2a O    22.2916  -16.0462
            35  C1a C    22.2922  -14.6304
BOND        35
            1     4   5 1
            2     5   6 1
            3     6   7 2
            4     7   8 1
            5     8   9 1
            6     4   9 1
            7     4  10 1
            8    10  11 1
            9     5  11 1
            10   10  12 1 #Up
            11   12  13 1
            12   13  14 2
            13   11  15 2
            14   13  16 1
            15    7  17 1
            16   16  18 1
            17   17  19 1
            18   18  20 2
            19   20  21 1
            20   21  22 1
            21   22  23 2
            22   18  23 1
            23   16  24 2
            24    6  25 1
            25   25  26 1
            26   25  27 2
            27   19  28 1
            28   19  29 1
            29   29  30 1
            30   30  31 1
            31   28  31 1
            32   19  32 1
            33   22  33 1
            34   24  34 1
            35   34  35 1

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