| Entry |
|
|---|
| Name |
Diphenylpyraline hydrochloride (JAN);
Hispril (TN);
Vena (TN)
|
|---|
| Formula |
C19H23NO. HCl
|
|---|
| Exact mass |
317.1546
|
|---|
| Mol weight |
317.853
|
|---|
| Structure |
     |
|---|
| Activity |
Antiallergic;
Histamine, H1-receptor antagonist
|
|---|
| Remark |
Therapeutic category: ATC code: |
|---|
| Target |
|
|---|
| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
|
|---|
| Interaction |
|
|---|
| Structure map |
| Histamine H1 receptor antagonists |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
44 Allergic agents
441 Antihistamines
4415 Diphenylpyralines
D01172 Diphenylpyraline hydrochloride (JAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA07 Diphenylpyraline
D01172 Diphenylpyraline hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H1-receptor [HSA:3269] [KO:K04149]
Diphenylpyraline [ATC:R06AA07]
D01172 Diphenylpyraline hydrochloride (JAN)
 |
|---|
| Other DBs |
CAS: 132-18-3 PubChem: DrugBank: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 22
1 C8x C 15.8965 -18.3777
2 C8x C 15.8965 -19.7781
3 C8x C 17.1122 -20.4783
4 C8x C 18.3208 -19.7781
5 C8y C 18.3208 -18.3777
6 C8x C 17.1122 -17.6775
7 C1c C 19.5341 -17.6783
8 C8y C 20.7462 -18.3795
9 O2a O 19.5351 -16.2779
10 C8x C 20.7398 -19.7779
11 C8x C 21.9519 -20.4789
12 C8x C 23.1653 -19.7798
13 C8x C 23.1663 -18.3794
14 C8x C 21.9540 -17.6782
15 C1y C 20.7485 -15.5788
16 C1x C 21.9589 -16.2788
17 C1x C 23.1722 -15.5796
18 N1y N 23.1733 -14.1792
19 C1x C 21.9609 -13.4780
20 C1x C 20.7478 -14.1773
21 C1a C 24.3866 -13.4799
22 X Cl 27.6442 -16.9632
BOND 23
1 4 5 1
2 5 6 2
3 6 1 1
4 8 10 2
5 10 11 1
6 11 12 2
7 12 13 1
8 13 14 2
9 14 8 1
10 9 15 1
11 5 7 1
12 7 8 1
13 1 2 2
14 7 9 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 15 1
21 2 3 1
22 18 21 1
23 3 4 2
|
|---|
