| Entry |
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| Name |
Olopatadine hydrochloride (JAN/USAN);
Allelock (TN);
Patanol (TN)
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| Product |
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| Generic |
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| Formula |
C21H23NO3. HCl
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| Exact mass |
373.1445
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| Mol weight |
373.8732
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| Structure |
     |
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| Activity |
Anti-allergic
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| Remark |
Therapeutic category: ATC code: |
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| Target |
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| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
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| Interaction |
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| Structure map |
| Histamine H1 receptor antagonists |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D01192 Olopatadine hydrochloride (JAN/USAN)
4 Agents affecting cellular function
44 Allergic agents
449 Miscellaneous
4490 Miscellaneous
D01192 Olopatadine hydrochloride (JAN/USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AC Antiallergic agents, excl. corticosteroids
R01AC08 Olopatadine
D01192 Olopatadine hydrochloride (JAN/USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GX Other antiallergics
S01GX09 Olopatadine
D01192 Olopatadine hydrochloride (JAN/USAN)
USP drug classification [BR:br08302]
Ophthalmic Agents
Ophthalmic Anti-allergy Agents
Olopatadine
D01192 Olopatadine hydrochloride (JAN/USAN)
Respiratory Tract Agents
Antihistamines
Histamine1 (H1) Receptor Antagonists, Mildly / Non-sedating
Olopatadine
D01192 Olopatadine hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H1-receptor [HSA:3269] [KO:K04149]
Olopatadine [ATC:R01AC08 S01GX09]
D01192 Olopatadine hydrochloride (JAN/USAN)
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| Other DBs |
CAS: 140462-76-6 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 26
1 O2x O 15.4452 -11.5273
2 C8y C 14.6008 -10.4147
3 C8y C 14.9369 -9.0542
4 C2y C 16.2014 -8.4745
5 C1x C 16.8548 -11.5526
6 C8y C 17.4583 -9.0985
7 C8y C 17.7456 -10.4710
8 C8x C 13.9270 -8.0831
9 C8y C 12.5814 -8.4723
10 C8x C 12.2453 -9.8328
11 C8x C 13.2551 -10.8036
12 C8x C 19.0804 -10.9093
13 C8x C 20.1275 -9.9723
14 C8x C 19.8404 -8.5998
15 C8x C 18.5053 -8.1615
16 C2b C 16.1531 -7.0958
17 C1b C 17.3804 -6.4128
18 C1b C 18.5520 -7.1142
19 N1c N 19.7775 -6.4323
20 C1a C 21.0156 -7.1729
21 C1a C 19.7996 -5.0603
22 C1b C 11.5808 -7.5102
23 C6a C 10.2132 -7.9060
24 O6a O 9.2093 -6.9413
25 O6a O 9.8773 -9.2674
26 X Cl 23.1026 -9.6929
BOND 27
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 2
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 19 21 1
24 9 22 1
25 22 23 1
26 23 24 1
27 23 25 2
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