KEGG   DRUG: Acetazolamide sodiumHelp
Entry
D01196                      Drug                                   

Name
Acetazolamide sodium (JAN);
Diamox (TN)
Product
  Generic
Formula
C4H5N4O3S2. Na
Exact mass
243.9701
Mol weight
244.2273
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01534  Carbonic anhydrase inhibitor
Remark
Therapeutic category: 2134
ATC code: S01EC01
Chemical structure group: DG01134
Product (DG01134): D00218<JP/US> D01196<JP/US>
Efficacy
Antiglaucoma, Carbonic anhydrase inhibitor
  Disease
Open-angle glaucoma [DS:H00612]
Comment
Sulfonamide derivative
Diuretic action
Target
  Pathway
hsa04964  Proximal tubule bicarbonate reclamation
Interaction
Drug interaction
Structure map
map07017  Sulfonamide derivatives - diuretics
map07033  Anticonvulsants
map07054  Antiglaucoma agents
map07055  Sulfonamide derivatives - overview
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EC Carbonic anhydrase inhibitors
     S01EC01 Acetazolamide
      D01196  Acetazolamide sodium (JAN) <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Carbonic Anhydrase Inhibitors
   Acetazolamide
    D01196  Acetazolamide sodium (JAN)
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Acetazolamide
    D01196  Acetazolamide sodium (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   213  Diuretics
    2134  Carbonic anhydrase inhibitors
     D01196  Acetazolamide sodium (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Aldehyde-lyases
    CA
     D01196  Acetazolamide sodium (JAN) <JP/US>
Drug classes of therapeutic agents [br08360.html]
 Neurological agents
  D01196
BRITE hierarchy
Other DBs
CAS: 1424-27-7
PubChem: 7848259
ChEBI: 31163
ChEMBL: CHEMBL1200814
DrugBank: DB00819
LigandBox: D01196
NIKKAJI: J24.636K
KCF data Show

ATOM        14
            1   N5x N    25.5209  -16.3791
            2   C8y C    25.9582  -15.0505
            3   S2x S    24.8212  -14.2224
            4   C8y C    23.6844  -15.0505
            5   N5x N    24.1217  -16.3791
            6   N1b N    27.1654  -14.3451
            7   C5a C    28.3702  -15.0373
            8   C1a C    29.5819  -14.3378
            9   O5a O    28.3733  -16.4368
            10  S4a S    22.2790  -15.0465
            11  O3c O    22.2790  -13.6470
            12  O3c O    20.8795  -15.0465
            13  N1a N    22.2790  -16.4461 #-
            14  Z   Na   19.6199  -17.1459 #+
BOND        13
            1     6   7 1
            2     1   2 2
            3     7   8 1
            4     2   3 1
            5     7   9 2
            6     3   4 1
            7     4   5 2
            8     5   1 1
            9     2   6 1
            10    4  10 1
            11   10  11 2
            12   10  12 2
            13   10  13 1

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