KEGG   DRUG: D01199Help
Entry
D01199                      Drug                                   

Name
Emtricitabine (JAN/USAN/INN);
Emtriva (TN)
Product
Formula
C8H10FN3O3S
Exact mass
247.0427
Mol weight
247.2467
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [treatment of HIV-1 and Hepatitis B infections] [DS:H00406 H00412]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Comment
nucleoside reverse transcriptase inhibitor (NRTI)
Target
RNA-directed DNA polymerase inhibitor [KO:K00986]
Interaction
Transporter inhibition: ABCC2 [HSA:1244], ABCC3 [HSA:8714]
Drug interaction
Structure map
Anti-HIV agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D01199  Emtricitabine (JAN/USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
     J05AF09 Emtricitabine
      D01199  Emtricitabine (JAN/USAN/INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTI)v
   Emtricitabine
    D01199  Emtricitabine (JAN/USAN/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HIV agent
   Reverse transcriptase inhibitor (RTI)
    Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs)
     Emtricitabine [ATC:J05AF09]
      D01199  Emtricitabine (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
143491-57-0
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        16
            1   N4y N    25.0103  -17.6390
            2   C1y C    23.6350  -18.1111
            3   C1y C    21.3970  -18.1111
            4   C1b C    20.1381  -17.4117
            5   O1a O    18.9492  -18.1111
            6   S2x S    21.8166  -19.4399
            7   O2x O    22.5160  -17.2718
            8   C1x C    23.2154  -19.4399
            9   C8x C    25.0206  -16.2402
            10  C8y C    26.2146  -15.5496
            11  C8y C    27.4684  -16.2582
            12  N5x N    27.4581  -17.6570
            13  C8y C    26.2641  -18.3476
            14  N1a N    28.6624  -15.5676
            15  X   F    26.1549  -14.1509
            16  O5x O    26.2538  -19.7463
BOND        17
            1     8   6 1
            2     4   5 1
            3     2   1 1 #Down
            4     3   4 1 #Down
            5     6   3 1
            6     1   9 1
            7     9  10 2
            8    10  11 1
            9    11  12 2
            10   12  13 1
            11   13   1 1
            12    3   7 1
            13   11  14 1
            14    7   2 1
            15   10  15 1
            16    2   8 1
            17   13  16 2

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