KEGG   DRUG: D01205Help
Entry
D01205                      Drug                                   

Name
Dexmedetomidine hydrochloride (JAN/USAN);
Precedex (TN)
Product
Formula
C13H16N2. HCl
Exact mass
236.108
Mol weight
236.7405
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Sedative
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CM Other hypnotics and sedatives
     N05CM18 Dexmedetomidine
      D01205  Dexmedetomidine hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1129  Others
     D01205  Dexmedetomidine hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha2-adrenergic receptor
     Dexmedetomidine
      D01205  Dexmedetomidine hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
145108-58-3
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        16
            1   X   Cl   27.3320  -22.4150
            2   C8y C    20.8462  -21.6678
            3   C1c C    22.0574  -20.9599
            4   C8y C    19.6349  -20.9599
            5   C8x C    20.8462  -23.0602
            6   C8y C    23.2859  -21.6678
            7   C1a C    22.0574  -19.5614
            8   C8y C    18.4180  -21.6678
            9   C1a C    19.6292  -19.5614
            10  C8x C    19.6349  -23.7624
            11  C8x C    23.3213  -23.0709
            12  N5x N    24.5990  -21.1978
            13  C8x C    18.4238  -23.0719
            14  C1a C    17.2070  -20.9657
            15  N4x N    24.6642  -23.4622
            16  C8x C    25.4403  -22.3076
BOND        16
            1     2   3 1
            2     2   4 2
            3     2   5 1
            4     3   6 1
            5     3   7 1 #Down
            6     4   8 1
            7     4   9 1
            8     5  10 2
            9     6  11 2
            10    6  12 1
            11    8  13 2
            12    8  14 1
            13   11  15 1
            14   12  16 2
            15   10  13 1
            16   15  16 1

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