KEGG   DRUG: D01226Help
Entry
D01226                      Drug                                   

Name
Sulpiride (JP16/USAN/INN);
Dogmatyl (TN)
Formula
C15H23N3O4S
Exact mass
341.1409
Mol weight
341.4258
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
Therapeutic category: 
ATC code: 
Comment
Benzamide derivatives
Target
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145];
dopamine D3-receptor antagonist [HSA:1814] [KO:K04146]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Antipsychotics
Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AL Benzamides
     N05AL01 Sulpiride
      D01226  Sulpiride (JP16/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   117  Psychotropics
    1179  Others
     D01226  Sulpiride (JP16/USAN/INN)
 2  Agents affecting individual organs
  23  Digestive organ agents
   232  Peptic ulcer agents
    2329  Others
     D01226  Sulpiride (JP16/USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Sulpiride
      D01226  Sulpiride (JP16/USAN/INN)
    dopamine D3-receptor
     Sulpiride
      D01226  Sulpiride (JP16/USAN/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01226  Sulpiride
  D01226  Sulpiride capsules
  D01226  Sulpiride tablets
BRITE hierarchy
Other DBs
CAS: 
15676-16-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C8y C    11.2700  -23.1000
            2   C8x C    11.2700  -21.7000
            3   C8x C    12.4600  -21.0000
            4   C8y C    13.7200  -21.7000
            5   C8y C    13.7200  -23.1000
            6   C8x C    12.4600  -23.8000
            7   C5a C    14.9100  -23.8000
            8   N1b N    16.1000  -23.1000
            9   O5a O    14.9100  -25.2000
            10  O2a O    14.9100  -21.0000
            11  C1b C    17.2900  -23.8000
            12  C1y C    18.4800  -23.1000
            13  C1x C    18.9000  -21.7700
            14  C1x C    20.3000  -21.7700
            15  C1x C    20.7900  -23.1000
            16  N1y N    19.6700  -23.9400
            17  C1b C    19.6700  -25.3400
            18  C1a C    20.8600  -26.0400
            19  S4a S    10.0800  -23.8000
            20  N1a N     8.8200  -24.5000
            21  O3c O     9.3800  -22.6100
            22  O3c O    11.0600  -24.7800
            23  C1a C    14.9100  -19.6000
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     7   9 2
            10    4  10 1
            11    8  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   12  16 1
            18   16  17 1
            19   17  18 1
            20    1  19 1
            21   19  20 1
            22   19  21 2
            23   19  22 2
            24   10  23 1

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