KEGG   DRUG: D01231Help
Entry
D01231                      Drug                                   

Name
Piroheptine hydrochloride (JAN);
Trimol (TN)
Formula
C22H25N. HCl
Exact mass
339.1754
Mol weight
339.9015
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian
Remark
Therapeutic category: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1169  Others
     D01231  Piroheptine hydrochloride (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Piroheptine
      D01231  Piroheptine hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
16378-22-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C1x C    16.4252  -11.3873
            2   C8y C    15.5808  -10.2747
            3   C8y C    15.9169   -8.9142
            4   C2y C    17.1814   -8.3345
            5   C1x C    17.8348  -11.4126
            6   C8y C    18.4383   -8.9585
            7   C8y C    18.7256  -10.3310
            8   C8x C    14.9070   -7.9431
            9   C8x C    13.5614   -8.3323
            10  C8x C    13.2253   -9.6928
            11  C8x C    14.2351  -10.6636
            12  C8x C    20.0604  -10.7693
            13  C8x C    21.1075   -9.8323
            14  C8x C    20.8204   -8.4598
            15  C8x C    19.4853   -8.0215
            16  C2y C    17.1331   -6.9558
            17  C1y C    18.2593   -6.0760
            18  N1y N    17.7706   -4.7330
            19  C1x C    16.3423   -4.7828
            20  C1x C    15.9484   -6.1566
            21  C1a C    19.6187   -6.4657
            22  C1b C    18.4279   -3.4969
            23  C1a C    19.8279   -3.4969
            24  X   Cl   24.0826   -9.5529
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 2
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   16  20 1
            24   17  21 1
            25   18  22 1
            26   22  23 1

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