| Entry |
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| Name |
Ampicillin hydrate (JP16);
Ampicillin trihydrate;
Amcill (TN)
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| Product |
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| Generic |
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| Formula |
C16H19N3O4S. 3H2O
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| Exact mass |
403.1413
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| Mol weight |
403.4506
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| Structure |
     |
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| Activity |
Antibacterial
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| Remark |
Therapeutic category: ATC code: |
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| Comment |
Semisynthetic penicillin: moderate spectrum penicillin
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| Target |
penicillin binding proteins inhibitor |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6131 Penicillins
D01251 Ampicillin hydrate (JP16)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
J01CA Penicillins with extended spectrum
J01CA01 Ampicillin
D01251 Ampicillin hydrate (JP16)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA19 Ampicillin
D01251 Ampicillin hydrate (JP16)
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Penicillins
Amino Derivative Penicillins
Ampicillin
D01251 Ampicillin hydrate (JP16)
Antiinfectives [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor
Penicillin binding proteins inhibitor
Penicillins
Ampicillin [ATC:J01CA01]
D01251 Ampicillin hydrate (JP16)
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| Other DBs |
CAS: 7177-48-2 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 27
1 C1y C 25.9451 -14.8660
2 C5x C 25.9451 -16.2704
3 N1y N 27.3495 -16.2704
4 C1y C 27.3495 -14.8660
5 C1y C 28.6836 -16.6916
6 C1z C 29.5261 -15.5681
7 S2x S 28.6836 -14.4446
8 C1a C 30.5093 -16.5512
9 C1a C 30.5093 -14.5850
10 C6a C 29.1751 -18.0257
11 O6a O 30.5794 -18.0257
12 O6a O 28.3324 -19.1492
13 N1b N 24.7514 -14.1638
14 C5a C 23.5577 -14.8660
15 O5x O 24.7514 -16.9725
16 O5a O 23.5577 -16.2704
17 C1c C 22.3386 -14.1687
18 C8y C 21.1466 -14.8637
19 N1a N 22.3386 -12.7679
20 C8x C 19.9334 -14.1633
21 C8x C 18.7203 -14.8637
22 C8x C 18.7203 -16.2645
23 C8x C 19.9334 -16.9649
24 C8x C 21.1466 -16.2645
25 O0 O 35.5115 -16.1114
26 O0 O 35.5115 -16.1114
27 O0 O 35.5115 -16.1114
BOND 26
1 1 2 1
2 2 3 1
3 3 4 1
4 1 4 1
5 3 5 1
6 5 6 1
7 6 7 1
8 4 7 1
9 6 8 1
10 6 9 1
11 5 10 1 #Down
12 10 11 1
13 10 12 2
14 1 13 1 #Up
15 13 14 1
16 2 15 2
17 14 16 2
18 14 17 1
19 17 18 1
20 17 19 1 #Up
21 18 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 18 24 1
BRACKET 1 33.5300 -17.0100 33.5300 -15.1900
1 35.9800 -15.1900 35.9800 -17.0100
1 3
ORIGINAL 1 26
REPEAT 1 27 28
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