KEGG   DRUG: D01292Help
Entry
D01292                      Drug                                   

Name
Medazepam (JP16/INN);
Pamnace (TN)
Formula
C16H15ClN2
Exact mass
270.0924
Mol weight
270.7567
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Benzodiazepines
Target
GABAA-receptor (benzodiazepine binding site) agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Interaction
Drug interaction
Structure map
GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA03 Medazepam
      D01292  Medazepam (JP16/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D01292  Medazepam (JP16/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site)
     Medazepam
      D01292  Medazepam (JP16/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01292  Medazepam
BRITE hierarchy
Other DBs
CAS: 
2898-12-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C2y C    19.9434  -14.3594
            2   C8y C    19.1013  -13.2498
            3   C8y C    19.4365  -11.8930
            4   N1y N    20.6975  -11.3149
            5   N2x N    21.3492  -14.3846
            6   C1x C    21.9511  -11.9372
            7   C1x C    22.2376  -13.3059
            8   C8x C    18.4294  -10.9246
            9   C8x C    17.0874  -11.3127
            10  C8y C    16.7522  -12.6695
            11  C8x C    17.7593  -13.6376
            12  X   Cl   15.3874  -13.0639
            13  C8y C    19.3089  -15.6091
            14  C8x C    17.9073  -15.6091
            15  C8x C    17.2073  -16.8216
            16  C8x C    17.9073  -18.0340
            17  C8x C    19.3089  -18.0340
            18  C8x C    20.0089  -16.8216
            19  C1a C    20.7192   -9.9400
BOND        21
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13   10  12 1
            14    1  13 1
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   13  18 2
            21    4  19 1

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