KEGG   DRUG: D01297Help
Entry
D01297                      Drug                                   

Name
Pirenzepine hydrochloride (USAN)
Formula
C19H21N5O2. 2HCl
Exact mass
423.1229
Mol weight
424.3242
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-ulcerative
Remark
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor M1 antagonist [HSA:1128] [KO:K04129]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse  
 
Interaction
Drug interaction
Structure map
Antiulcer drugs
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A02 DRUGS FOR ACID RELATED DISORDERS
   A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
    A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
     A02BX03 Pirenzepine
      D01297  Pirenzepine hydrochloride (USAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Pirenzepine
    D01297  Pirenzepine hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor M1
     Pirenzepine
      D01297  Pirenzepine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
29868-97-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   X   Cl   36.4585  -18.1487
            2   C5x C    29.0500  -23.2400
            3   C8y C    28.2100  -22.1200
            4   C8y C    28.5600  -20.7900
            5   N1y N    29.8200  -20.2300
            6   N1x N    30.4500  -23.2400
            7   C8y C    31.0800  -20.8600
            8   C8y C    31.3600  -22.1900
            9   C8x C    27.5100  -19.8100
            10  C8x C    26.1800  -20.2300
            11  C8x C    25.8300  -21.5600
            12  C8x C    26.8800  -22.5400
            13  C8x C    32.6900  -22.6100
            14  C8x C    33.7400  -21.7000
            15  C8x C    33.4600  -20.3000
            16  N5x N    32.1300  -19.8800
            17  O5x O    28.4200  -24.5000
            18  C5a C    29.8200  -18.8300
            19  C1b C    31.0100  -18.1300
            20  O5a O    28.6300  -18.1300
            21  N1y N    31.0100  -16.7300
            22  C1x C    32.2700  -16.0300
            23  C1x C    32.2700  -14.6300
            24  N1y N    31.0100  -13.9300
            25  C1x C    29.8200  -14.6300
            26  C1x C    29.8200  -16.0300
            27  C1a C    31.0100  -12.5300
            28  X   Cl   36.4585  -18.1487
BOND        29
            1     4   5 1
            2     2   6 1
            3     5   7 1
            4     3   4 1
            5     6   8 1
            6     2   3 1
            7     7   8 1
            8     4   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12    3  12 2
            13    8  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17    7  16 2
            18    2  17 2
            19    5  18 1
            20   18  19 1
            21   18  20 2
            22   19  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   21  26 1
            29   24  27 1
BRACKET     1    34.7900  -19.1800   34.7900  -17.0100
            1    37.3100  -17.0100   37.3100  -19.1800
            1  2
 ORIGINAL  1    1
 REPEAT    1   28

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