KEGG   DRUG: Pirenzepine hydrochlorideHelp
Entry
D01297                      Drug                                   

Name
Pirenzepine hydrochloride (USAN)
Formula
C19H21N5O2. 2HCl
Exact mass
423.1229
Mol weight
424.3242
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Remark
ATC code: 
Chemical group: 
Activity
Antisecretory (gastric acid), Anti-ulcerative, Muscarinic antagonist
Comment
Tricyclic compound
Target
CHRM1 [HSA:1128] [KO:K04129]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Interaction
Drug interaction
Structure map
Antiulcer drugs
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A02 DRUGS FOR ACID RELATED DISORDERS
   A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
    A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
     A02BX03 Pirenzepine
      D01297  Pirenzepine hydrochloride (USAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Pirenzepine
    D01297  Pirenzepine hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor M1
     Pirenzepine
      D01297  Pirenzepine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
29868-97-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   X   Cl   36.4585  -18.1487
            2   C5x C    29.0500  -23.2400
            3   C8y C    28.2100  -22.1200
            4   C8y C    28.5600  -20.7900
            5   N1y N    29.8200  -20.2300
            6   N1x N    30.4500  -23.2400
            7   C8y C    31.0800  -20.8600
            8   C8y C    31.3600  -22.1900
            9   C8x C    27.5100  -19.8100
            10  C8x C    26.1800  -20.2300
            11  C8x C    25.8300  -21.5600
            12  C8x C    26.8800  -22.5400
            13  C8x C    32.6900  -22.6100
            14  C8x C    33.7400  -21.7000
            15  C8x C    33.4600  -20.3000
            16  N5x N    32.1300  -19.8800
            17  O5x O    28.4200  -24.5000
            18  C5a C    29.8200  -18.8300
            19  C1b C    31.0100  -18.1300
            20  O5a O    28.6300  -18.1300
            21  N1y N    31.0100  -16.7300
            22  C1x C    32.2700  -16.0300
            23  C1x C    32.2700  -14.6300
            24  N1y N    31.0100  -13.9300
            25  C1x C    29.8200  -14.6300
            26  C1x C    29.8200  -16.0300
            27  C1a C    31.0100  -12.5300
            28  X   Cl   36.4585  -18.1487
BOND        29
            1     4   5 1
            2     2   6 1
            3     5   7 1
            4     3   4 1
            5     6   8 1
            6     2   3 1
            7     7   8 1
            8     4   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12    3  12 2
            13    8  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17    7  16 2
            18    2  17 2
            19    5  18 1
            20   18  19 1
            21   18  20 2
            22   19  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   21  26 1
            29   24  27 1
BRACKET     1    34.7900  -19.1800   34.7900  -17.0100
            1    37.3100  -17.0100   37.3100  -19.1800
            1  2
 ORIGINAL  1    1
 REPEAT    1   28

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