KEGG   DRUG: D01304Help
Entry
D01304                      Drug                                   

Name
Amezinium metilsulfate (JAN);
Risumic (TN)
Formula
C11H12N3O. CH3SO4
Exact mass
313.0732
Mol weight
313.3296
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
ATC code: 
Comment
Norepinephrine reuptake inhibitor
Target
monoamine oxidase (MAO) inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D01304  Amezinium metilsulfate (JAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA25 Amezinium metilsulfate
      D01304  Amezinium metilsulfate (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO) [HSA:4128 4129] [KO:K00274]
    Amezinium metilsulfate [ATC:C01CA25]
     D01304  Amezinium metilsulfate (JAN)
BRITE hierarchy
Other DBs
CAS: 
30578-37-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8x C    19.2675  -15.5914
            2   C8y C    19.2675  -16.9909
            3   C8x C    20.4825  -17.6907
            4   C8x C    21.6903  -16.9909
            5   C8x C    21.6903  -15.5914
            6   C8x C    20.4825  -14.8916
            7   N5y N    18.0558  -17.6914 #+
            8   C8y C    16.8462  -16.9886
            9   C8x C    15.6345  -17.6890
            10  C8y C    15.6353  -19.0886
            11  C8x C    16.8477  -19.7877
            12  N5x N    18.0593  -19.0874
            13  O2a O    16.8477  -15.3790
            14  N1a N    14.4236  -19.7890
            15  C1a C    18.0605  -14.6806
            16  S4a S    26.7406  -17.6792
            17  O2a O    25.3541  -17.6792
            18  O1d O    26.7347  -16.0588
            19  O1d O    26.7347  -19.0363
            20  O1d O    28.0275  -17.6792 #-
            21  C1a C    24.1726  -17.0006
BOND        21
            1     7   8 2
            2     8   9 1
            3     9  10 2
            4    10  11 1
            5    11  12 2
            6    12   7 1
            7     5   6 2
            8     8  13 1
            9     6   1 1
            10   10  14 1
            11   13  15 1
            12    2   7 1
            13    1   2 2
            14    2   3 1
            15    3   4 2
            16    4   5 1
            17   16  17 1
            18   16  18 2
            19   16  19 2
            20   16  20 1
            21   17  21 1

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