| Entry |
|
|---|
| Name |
Mequitazine (JP16/INN);
Kitazemin (TN)
|
|---|
| Formula |
C20H22N2S
|
|---|
| Exact mass |
322.1504
|
|---|
| Mol weight |
322.4671
|
|---|
| Structure |
     |
|---|
| Activity |
Antihistaminic
|
|---|
| Remark |
Same as: Therapeutic category: ATC code: |
|---|
| Target |
|
|---|
| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
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| Structure map |
| Histamine H1 receptor antagonists |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
44 Allergic agents
441 Antihistamines
4413 Phenothiazines
D01324 Mequitazine (JP16/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AD Phenothiazine derivatives
R06AD07 Mequitazine
D01324 Mequitazine (JP16/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H1-receptor [HSA:3269] [KO:K04149]
Mequitazine [ATC:R06AD07]
D01324 Mequitazine (JP16/INN)
 |
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| Other DBs |
CAS: 29216-28-2 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 23
1 C1x C 23.4130 -15.6918
2 N1y N 24.8526 -14.8141
3 C1y C 22.6816 -14.6444
4 C1x C 24.8526 -13.5735
5 C1x C 26.3564 -15.6216
6 C1y C 24.0978 -13.8077
7 C1x C 24.1035 -12.8187
8 C1x C 25.6602 -14.5097
9 C8x C 17.8213 -17.4339
10 C8x C 17.8213 -18.8339
11 C8x C 19.0367 -19.5339
12 C8x C 19.0367 -16.7339
13 C8y C 20.2449 -17.4339
14 C8y C 20.2388 -18.8339
15 S2x S 21.4483 -19.5392
16 N1y N 21.4603 -16.7392
17 C8y C 22.6698 -17.4443
18 C8y C 22.6570 -18.8407
19 C8x C 23.8600 -19.5497
20 C8x C 25.0756 -18.8626
21 C8x C 25.0883 -17.4662
22 C8x C 23.8853 -16.7572
23 C1b C 21.4663 -15.3392
BOND 27
1 10 11 2
2 11 14 1
3 13 12 1
4 12 9 2
5 2 5 1
6 3 6 1
7 4 7 1
8 5 8 1
9 13 14 2
10 14 15 1
11 15 18 1
12 17 16 1
13 16 13 1
14 6 7 1
15 6 8 1
16 1 2 1
17 1 3 1
18 2 4 1
19 17 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 22 17 1
25 9 10 1
26 16 23 1
27 23 3 1
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