KEGG   DRUG: D01333Help
Entry
D01333                      Drug                                   

Name
Urapidil (JP16/INN);
Ebrantil (TN)
Formula
C20H29N5O3
Exact mass
387.227
Mol weight
387.476
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
    C02CA Alpha-adrenoreceptor antagonists
     C02CA06 Urapidil
      D01333  Urapidil (JP16/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01333  Urapidil (JP16/INN)
  25  Urogenital and anal organ agents
   259  Miscellaneous
    2590  Miscellaneous
     D01333  Urapidil (JP16/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Urapidil
      D01333  Urapidil (JP16/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01333  Urapidil
BRITE hierarchy
Other DBs
CAS: 
34661-75-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C8x C    17.0199  -22.1795
            2   C8x C    17.0199  -20.7792
            3   C8y C    18.2356  -20.0790
            4   C8y C    19.4442  -20.7792
            5   C8x C    19.4442  -22.1795
            6   C8x C    18.2356  -22.8797
            7   N1y N    20.6573  -20.0798
            8   C1x C    20.6560  -18.6863
            9   C1x C    21.8693  -17.9869
            10  N1y N    23.0816  -18.6881
            11  C1x C    23.0804  -20.0885
            12  C1x C    21.8672  -20.7877
            13  C1b C    24.2947  -17.9888
            14  C1b C    25.5070  -18.6898
            15  C1b C    26.7203  -17.9907
            16  N1b N    27.9325  -18.6917
            17  C8y C    29.1458  -17.9923
            18  C8x C    29.1429  -16.5921
            19  C8y C    30.3562  -15.8928
            20  N4y N    31.5685  -16.5940
            21  C8y C    31.5675  -17.9944
            22  N4y N    30.3542  -18.6936
            23  C1a C    30.3521  -20.0939
            24  O5x O    32.7796  -18.6954
            25  C1a C    32.7818  -15.8947
            26  O5x O    30.3572  -14.4924
            27  O2a O    18.2373  -18.6786
            28  C1a C    17.0553  -17.9940
BOND        30
            1    13  14 1
            2     4   7 1
            3    14  15 1
            4     1   2 2
            5    15  16 1
            6     2   3 1
            7    16  17 1
            8     3   4 2
            9     4   5 1
            10    5   6 2
            11    7   8 1
            12    8   9 1
            13   17  18 2
            14   18  19 1
            15   19  20 1
            16   20  21 1
            17   21  22 1
            18   22  17 1
            19    9  10 1
            20   22  23 1
            21   10  11 1
            22   21  24 2
            23   11  12 1
            24   20  25 1
            25   12   7 1
            26   19  26 2
            27    6   1 1
            28    3  27 1
            29   10  13 1
            30   27  28 1

» Japanese version   » Back

DBGET integrated database retrieval system