KEGG   DRUG: D01336Help
Entry
D01336                      Drug                                   

Name
Carbinoxamine maleate (JAN/USP);
Clistin (TN);
Karbinal er (TN)
Product
  Generic
Formula
C16H19ClN2O. C4H4O4
Exact mass
406.1296
Mol weight
406.86
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihistaminic
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AA Aminoalkyl ethers
     R06AA08 Carbinoxamine
      D01336  Carbinoxamine maleate (JAN/USP)
USP drug classification [BR:br08302]
 Respiratory Tract/Pulmonary Agents
  Antihistamines
   Carbinoxamine
    D01336  Carbinoxamine maleate (JAN/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for otolaryngologic use
  69 Oral medicine for nasal inflammation
   D01336  Carbinoxamine maleate (JAN/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Carbinoxamine
    D01336  Carbinoxamine maleate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Carbinoxamine
      D01336  Carbinoxamine maleate (JAN/USP)
BRITE hierarchy
Other DBs
CAS: 
3505-38-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C6a C    34.1191  -18.0091
            2   C2b C    33.4156  -16.8836
            3   O6a O    33.4156  -19.2049
            4   O6a O    35.4556  -18.0091
            5   C2b C    31.7977  -16.8836
            6   C6a C    31.0942  -18.0091
            7   O6a O    29.7577  -18.0091
            8   O6a O    31.7977  -19.2049
            9   C8x C    19.9093  -17.0242
            10  C8y C    19.9093  -18.4311
            11  C8x C    21.1277  -19.1346
            12  C8x C    22.3462  -18.4311
            13  C8y C    22.3462  -17.0242
            14  C8x C    21.1277  -16.3208
            15  C8x C    24.7830  -18.4311
            16  C8y C    24.7830  -17.0242
            17  C1c C    23.5646  -16.3208
            18  C8x C    26.0014  -19.1346
            19  C8x C    27.2198  -18.4311
            20  C8x C    27.2198  -17.0242
            21  N5x N    26.0014  -16.3208
            22  X   Cl   18.6910  -19.1346
            23  O2a O    23.5646  -14.9139
            24  C1b C    24.7851  -14.2092
            25  C1b C    25.9875  -14.9036
            26  N1c N    27.1801  -14.2151
            27  C1a C    28.3775  -14.9066
            28  C1a C    27.1803  -12.8037
BOND        28
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 2
            5     5   6 1
            6     6   7 1
            7     6   8 2
            8     9  10 2
            9    10  11 1
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13    9  14 1
            14   15  16 1
            15   16  17 1
            16   13  17 1
            17   15  18 2
            18   18  19 1
            19   19  20 2
            20   20  21 1
            21   16  21 2
            22   10  22 1
            23   17  23 1
            24   23  24 1
            25   24  25 1
            26   25  26 1
            27   26  27 1
            28   26  28 1

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