| Entry |
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| Name |
Chlorhexidine hydrochloride (JP18/USP);
Dantroche hibitane (TN) |
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| Formula |
C22H30Cl2N10. 2HCl
|
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| Exact mass |
576.1566
|
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| Mol weight |
578.3685
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| Structure |
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| Simcomp |
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| Remark |
| Product (DG00001): | D00858<JP/US> |
| Product (mixture): | D04425<JP> |
|
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| Efficacy |
Antibacterial, Disinfectant, Cell membrane function inhibitor |
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| Comment |
Biguanide
|
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| Target |
Lipopolysaccharide
Lipoteichoic acid |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB03 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
B BLOOD AND BLOOD FORMING ORGANS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05C IRRIGATING SOLUTIONS
B05CA Antiinfectives
B05CA02 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
D DERMATOLOGICALS
D08 ANTISEPTICS AND DISINFECTANTS
D08A ANTISEPTICS AND DISINFECTANTS
D08AC Biguanides and amidines
D08AC02 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
D09 MEDICATED DRESSINGS
D09A MEDICATED DRESSINGS
D09AA Medicated dressings with antiinfectives
D09AA12 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
R RESPIRATORY SYSTEM
R02 THROAT PREPARATIONS
R02A THROAT PREPARATIONS
R02AA Antiseptics
R02AA05 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AX Other antiinfectives
S01AX09 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA09 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA04 Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
54 Disinfectants (incl. special bandages)
D01345 Chlorhexidine hydrochloride (JP18/USP)
Agents for dental and stomatological use
73 Stomatologic and laryngologic remedies (incl. toche without claims for cough and phlegm)
D01345 Chlorhexidine hydrochloride (JP18/USP)
75 Toothache and pyorrhea remedies
D01345 Chlorhexidine hydrochloride (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Chlorhexidine
D01345 Chlorhexidine hydrochloride (JP18/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01345 Chlorhexidine hydrochloride
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| Other DBs |
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| KCF data |
ATOM 36
1 C8y C 14.4119 -15.6024
2 N1b N 15.6268 -16.2923
3 C8x C 13.2047 -16.3000
4 C8x C 14.4119 -14.1995
5 C2c C 16.8338 -15.5947
6 C8x C 11.9897 -15.6024
7 C8x C 13.2047 -13.4939
8 N1b N 18.0488 -16.2923
9 N2a N 16.8338 -14.1995
10 C8y C 11.9897 -14.1995
11 C2c C 19.2635 -15.5947
12 X Cl 10.7768 -13.4939
13 N1b N 20.4784 -16.2923
14 N2a N 19.2635 -14.1915
15 C1b C 21.6934 -15.5947
16 C1b C 22.9083 -16.2923
17 C1b C 24.1233 -15.5947
18 C1b C 25.3381 -16.2923
19 C1b C 26.5451 -15.5947
20 C1b C 27.7600 -16.2843
21 N1b N 28.9750 -15.5867
22 C2c C 30.1899 -16.2843
23 N1b N 31.4047 -15.5867
24 N2a N 30.1899 -17.6875
25 C2c C 32.6196 -16.2843
26 N1b N 33.8345 -15.5867
27 N2a N 32.6196 -17.6875
28 C8y C 35.0415 -16.2843
29 C8x C 35.1038 -17.6795
30 C8x C 36.2488 -15.5790
31 C8x C 36.2488 -18.3771
32 C8x C 37.4637 -16.2766
33 C8y C 37.4637 -17.6718
34 X Cl 38.6784 -18.3771
35 X Cl 37.5900 -14.4200
36 X Cl 37.5900 -14.4200
BOND 35
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 2
9 6 10 2
10 8 11 1
11 10 12 1
12 11 13 1
13 11 14 2
14 13 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 21 22 1
22 22 23 1
23 22 24 2
24 23 25 1
25 25 26 1
26 25 27 2
27 26 28 1
28 28 29 2
29 28 30 1
30 29 31 1
31 30 32 2
32 31 33 2
33 33 34 1
34 7 10 1
35 32 33 1
BRACKET 1 36.0500 -15.1200 36.0500 -13.7200
1 38.3600 -13.7200 38.3600 -15.1200
1 2
ORIGINAL 1 35
REPEAT 1 36
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