KEGG   DRUG: D01347Help
Entry
D01347                      Drug                                   

Name
Tramazoline hydrochloride (JAN/USAN);
Towk (TN)
Formula
C13H17N3. HCl
Exact mass
251.1189
Mol weight
251.7551
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Adrenergic
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor agonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AA Sympathomimetics, plain
     R01AA09 Tramazoline
      D01347  Tramazoline hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   132  Otic and nasal agents
    1324  Otolaryngologic vasoconstrictors
     D01347  Tramazoline hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Tramazoline
      D01347  Tramazoline hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
3715-90-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   X   Cl   29.8200  -27.7900
            2   C1x C    21.7700  -26.2500
            3   C1x C    21.7700  -27.6500
            4   C1x C    22.9824  -28.3500
            5   C8y C    24.1949  -27.6500
            6   C8y C    24.1949  -26.2500
            7   C1x C    22.9824  -25.5500
            8   C8x C    25.4073  -28.3500
            9   C8x C    26.6197  -27.6500
            10  C8x C    26.6197  -26.2500
            11  C8y C    25.4073  -25.5500
            12  N1b N    25.4073  -24.1500
            13  C2y C    26.6218  -23.4488
            14  N1x N    27.9323  -23.8800
            15  C1x C    28.7495  -22.7673
            16  C1x C    27.9438  -21.6463
            17  N2x N    26.6286  -22.0661
BOND        18
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     5   6 1
            5     6   7 1
            6     2   7 1
            7     5   8 2
            8     8   9 1
            9     9  10 2
            10   10  11 1
            11    6  11 2
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   13  17 2

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