KEGG   DRUG: D01349Help
Entry
D01349                      Drug                                   

Name
Pirbuterol hydrochloride (JAN/USAN)
Formula
C12H20N2O3. 2HCl
Exact mass
312.1007
Mol weight
313.2207
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Remark
ATC code: 
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AC Selective beta-2-adrenoreceptor agonists
     R03AC08 Pirbuterol
      D01349  Pirbuterol hydrochloride (JAN/USAN)
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CC Selective beta-2-adrenoreceptor agonists
     R03CC07 Pirbuterol
      D01349  Pirbuterol hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor [HSA:154] [KO:K04142]
     Pirbuterol [ATC:R03AC08 R03CC07]
      D01349  Pirbuterol hydrochloride (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
38029-10-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   X   Cl   25.4800  -16.6600
            2   C8y C    15.3300  -16.8000
            3   N5x N    14.0700  -17.5000
            4   C1c C    16.5200  -17.5000
            5   C8x C    15.3300  -15.4000
            6   C8y C    12.8800  -16.8000
            7   C1b C    17.7100  -16.8000
            8   O1a O    16.5200  -18.9000
            9   C8x C    14.0700  -14.7000
            10  C8y C    12.8800  -15.4000
            11  C1b C    11.6900  -17.5000
            12  N1b N    18.9000  -17.5000
            13  O1a O    11.6900  -14.7000
            14  O1a O    10.3600  -16.8000
            15  C1d C    20.1600  -16.8000
            16  C1a C    21.3500  -16.1000
            17  C1a C    20.8600  -17.9900
            18  C1a C    19.4600  -15.6100
            19  X   Cl   25.4800  -16.6600
BOND        17
            1     2   3 1
            2     2   4 1
            3     2   5 2
            4     3   6 2
            5     4   7 1
            6     4   8 1
            7     5   9 1
            8     6  10 1
            9     6  11 1
            10    7  12 1
            11   10  13 1
            12   11  14 1
            13   12  15 1
            14    9  10 2
            15   15  16 1
            16   15  17 1
            17   15  18 1
BRACKET     1    23.7300  -17.4300   23.7300  -15.7500
            1    26.3900  -15.7500   26.3900  -17.4300
            1  2
 ORIGINAL  1    1
 REPEAT    1   19

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