KEGG   DRUG: D01350Help
Entry
D01350                      Drug                                   

Name
Streptomycin sulfate (JP16/USP);
Streptomycin sulfate (TN)
Product
  Generic
Formula
(C21H39N7O12)2. 3H2SO4
Exact mass
1456.4335
Mol weight
1457.3836
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial [tuberculostatic]
Remark
Therapeutic category: 
ATC code: 
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Aminoglycosides
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   616  Acting mainly on acid-fast bacteria
    6161  Streptomycin antibiotics
     D01350  Streptomycin sulfate (JP16/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA04 Streptomycin
      D01350  Streptomycin sulfate (JP16/USP)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GA Streptomycins
     J01GA01 Streptomycin
      D01350  Streptomycin sulfate (JP16/USP)
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Streptomycin
    D01350  Streptomycin sulfate (JP16/USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor [KO:K01977]
    Aminoglycosides
     Streptomycin [ATC:A07AA04 J01GA01]
      D01350  Streptomycin sulfate (JP16/USP)
BRITE hierarchy
Other DBs
CAS: 
3810-74-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        95
            1   O1d O    16.9199  -15.1376
            2   S4a S    18.3197  -15.1376
            3   O1d O    18.3126  -16.5374
            4   O1d O    19.7196  -15.1376
            5   O1d O    18.3126  -13.7377
            6   C1y C     7.9748  -17.3139
            7   C1y C     8.3840  -16.0619
            8   C1z C     6.6623  -17.3139
            9   O2a O     9.6542  -18.4157
            10  O2a O     9.9192  -14.7014
            11  O2x O     7.3126  -15.2974
            12  C1y C     6.2652  -16.0619
            13  C4a C     5.3562  -18.0424
            14  O1a O     6.6684  -18.5720
            15  C1y C     8.5706  -20.4924
            16  C1y C     9.8890  -13.0759
            17  C1a C     5.0190  -15.6525
            18  O4a O     4.2303  -17.3741
            19  C1y C     8.5706  -21.8167
            20  O2x O     7.4208  -19.8364
            21  C1y C     8.7572  -12.4078
            22  C1y C    11.0388  -12.4078
            23  C1y C     7.4208  -22.4850
            24  C1y C     6.2891  -20.4924
            25  C1y C     8.7572  -11.0835
            26  N1b N     6.9273  -13.2264
            27  C1y C    11.0388  -11.0835
            28  O1a O    12.1705  -13.0580
            29  C1y C     6.2891  -21.8167
            30  O1a O     7.4208  -23.7973
            31  C1b C     5.1575  -19.8364
            32  C1y C     9.8890  -10.4272
            33  O1a O     7.8409  -10.3508
            34  C2c C     5.7955  -12.5703
            35  O1a O    12.1705  -10.4213
            36  O1a O     5.1513  -22.4670
            37  O1a O     4.0196  -20.4924
            38  N1b N     9.8830   -9.1149
            39  N1a N     4.6578  -13.2204
            40  N2a N     5.8015  -11.2581
            41  C2c C     8.7513   -8.4648
            42  N2a N     8.7452   -7.1585
            43  N1a N     7.6195   -9.1209
            44  N1b N     9.7777  -22.5113
            45  C1a C    10.9870  -21.8106
            46  O1d O    16.9199  -15.1376
            47  S4a S    18.3197  -15.1376
            48  O1d O    18.3126  -16.5374
            49  O1d O    19.7196  -15.1376
            50  O1d O    18.3126  -13.7377
            51  O1d O    16.9199  -15.1376
            52  S4a S    18.3197  -15.1376
            53  O1d O    18.3126  -16.5374
            54  O1d O    19.7196  -15.1376
            55  O1d O    18.3126  -13.7377
            56  C1y C     7.9748  -17.3139
            57  C1y C     8.3840  -16.0619
            58  O2a O     9.9192  -14.7014
            59  C1y C     9.8890  -13.0759
            60  C1y C     8.7572  -12.4078
            61  C1y C     8.7572  -11.0835
            62  C1y C     9.8890  -10.4272
            63  N1b N     9.8830   -9.1149
            64  C2c C     8.7513   -8.4648
            65  N2a N     8.7452   -7.1585
            66  N1a N     7.6195   -9.1209
            67  C1y C    11.0388  -11.0835
            68  C1y C    11.0388  -12.4078
            69  O1a O    12.1705  -13.0580
            70  O1a O    12.1705  -10.4213
            71  O1a O     7.8409  -10.3508
            72  N1b N     6.9273  -13.2264
            73  C2c C     5.7955  -12.5703
            74  N1a N     4.6578  -13.2204
            75  N2a N     5.8015  -11.2581
            76  O2x O     7.3126  -15.2974
            77  C1y C     6.2652  -16.0619
            78  C1z C     6.6623  -17.3139
            79  C4a C     5.3562  -18.0424
            80  O4a O     4.2303  -17.3741
            81  O1a O     6.6684  -18.5720
            82  C1a C     5.0190  -15.6525
            83  O2a O     9.6542  -18.4157
            84  C1y C     8.5706  -20.4924
            85  C1y C     8.5706  -21.8167
            86  C1y C     7.4208  -22.4850
            87  C1y C     6.2891  -21.8167
            88  O1a O     5.1513  -22.4670
            89  C1y C     6.2891  -20.4924
            90  O2x O     7.4208  -19.8364
            91  C1b C     5.1575  -19.8364
            92  O1a O     4.0196  -20.4924
            93  O1a O     7.4208  -23.7973
            94  N1b N     9.7777  -22.5113
            95  C1a C    10.9870  -21.8106
BOND        96
            1     1   2 1
            2     2   3 2
            3     2   4 1
            4     2   5 2
            5    46  47 1
            6    47  48 2
            7    47  49 1
            8    47  50 2
            9    51  52 1
            10   52  53 2
            11   52  54 1
            12   52  55 2
            13    6   7 1
            14    6   8 1
            15    6   9 1 #Down
            16    7  10 1 #Up
            17    7  11 1
            18    8  12 1
            19    8  13 1 #Up
            20    8  14 1
            21   15   9 1 #Up
            22   16  10 1 #Down
            23   12  17 1 #Down
            24   13  18 2
            25   15  19 1
            26   15  20 1
            27   16  21 1
            28   16  22 1
            29   19  23 1
            30   20  24 1
            31   21  25 1
            32   21  26 1 #Up
            33   22  27 1
            34   22  28 1 #Up
            35   23  29 1
            36   23  30 1 #Down
            37   24  31 1 #Down
            38   25  32 1
            39   25  33 1 #Down
            40   26  34 1
            41   27  35 1 #Down
            42   29  36 1 #Up
            43   31  37 1
            44   32  38 1 #Up
            45   34  39 1
            46   34  40 2
            47   38  41 1
            48   41  42 2
            49   41  43 1
            50   11  12 1
            51   24  29 1
            52   27  32 1
            53   19  44 1 #Up
            54   44  45 1
            55   56  57 1
            56   56  78 1
            57   56  83 1 #Down
            58   57  58 1 #Up
            59   57  76 1
            60   78  77 1
            61   78  79 1 #Up
            62   78  81 1
            63   84  83 1 #Up
            64   59  58 1 #Down
            65   77  82 1 #Down
            66   79  80 2
            67   84  85 1
            68   84  90 1
            69   59  60 1
            70   59  68 1
            71   85  86 1
            72   90  89 1
            73   60  61 1
            74   60  72 1 #Up
            75   68  67 1
            76   68  69 1 #Up
            77   86  87 1
            78   86  93 1 #Down
            79   89  91 1 #Down
            80   61  62 1
            81   61  71 1 #Down
            82   72  73 1
            83   67  70 1 #Down
            84   87  88 1 #Up
            85   91  92 1
            86   62  63 1 #Up
            87   73  74 1
            88   73  75 2
            89   63  64 1
            90   64  65 2
            91   64  66 1
            92   76  77 1
            93   89  87 1
            94   67  62 1
            95   85  94 1 #Up
            96   94  95 1
BRACKET     1    15.5400  -17.5000   15.5400  -12.8800
            1    21.0000  -12.8800   21.0000  -17.5000
            1  3
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1   46  47  48  49  50  51  52  53  54  55
            2     2.2400  -24.4300    2.2400   -6.3000
            2    13.7900   -6.3000   13.7900  -24.4300
            2  2
 ORIGINAL  2    6   7  10  16  21  25  32  38  41  42  43  27  22  28  35  33
            2   26  34  39  40  11  12   8  13  18  14  17   9  15  19  23  29
            2   36  24  20  31  37  30  44  45
 REPEAT    2   56  57  58  59  60  61  62  63  64  65  66  67  68  69  70  71
            2   72  73  74  75  76  77  78  79  80  81  82  83  84  85  86  87
            2   88  89  90  91  92  93  94  95

» Japanese version   » Back

DBGET integrated database retrieval system