KEGG   DRUG: D01354Help
Entry
D01354                      Drug                                   
Name
Fludiazepam (JP16/INN);
Erispan (TN)
Formula
C16H12ClFN2O
Exact mass
302.0622
Mol weight
302.7307
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Tranquilizer [minor]
Remark
Therapeutic category: 
ATC code: 
Comment
Benzodiazepines
Target
GABAA-receptor (benzodiazepine binding site) agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Interaction
Drug interaction
Structure map
GABA-A receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D01354  Fludiazepam (JP16/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA17 Fludiazepam
      D01354  Fludiazepam (JP16/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site) [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05176 K05177 K05178 K05179 K05180 K05181 K05182 K05183 K05184 K05185 K05186 K05187 K05188 K05189 K05192]
     Fludiazepam [ATC:N05BA17]
      D01354  Fludiazepam (JP16/INN)
BRITE hierarchy
Other DBs
CAS: 
3900-31-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C2y C    13.7834  -11.9094
            2   C8y C    12.9413  -10.7998
            3   C8y C    13.2765   -9.4430
            4   N1y N    14.5375   -8.8649
            5   N2x N    15.1892  -11.9346
            6   C5x C    15.7911   -9.4872
            7   C1x C    16.0776  -10.8559
            8   C8x C    12.2694   -8.4746
            9   C8x C    10.9274   -8.8627
            10  C8y C    10.5922  -10.2195
            11  C8x C    11.5993  -11.1876
            12  O5x O    16.8352   -8.5528
            13  X   Cl    9.2274  -10.6139
            14  C8y C    13.1489  -13.1591
            15  C8x C    11.7473  -13.1591
            16  C8x C    11.0473  -14.3716
            17  C8x C    11.7473  -15.5840
            18  C8x C    13.1489  -15.5840
            19  C8y C    13.8489  -14.3716
            20  X   F    15.2598  -14.3717
            21  C1a C    14.5592   -7.4900
BOND        23
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   14  19 2
            22   19  20 1
            23    4  21 1

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