KEGG   DRUG: D01360Help
Entry
D01360                      Drug                                   

Name
Clenbuterol hydrochloride (JAN/USP);
Spiropent (TN)
Formula
C12H18Cl2N2O. HCl
Exact mass
312.0563
Mol weight
313.6511
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator;
beta2-Sympathomimetic [DS:H00079]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Comment
long-acting beta-adrenoceptor agonist (LABA)
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AC Selective beta-2-adrenoreceptor agonists
     R03AC14 Clenbuterol
      D01360  Clenbuterol hydrochloride (JAN/USP)
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CC Selective beta-2-adrenoreceptor agonists
     R03CC13 Clenbuterol
      D01360  Clenbuterol hydrochloride (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   225  Bronchodilators
    2259  Others
     D01360  Clenbuterol hydrochloride (JAN/USP)
  25  Urogenital and anal organ agents
   259  Miscellaneous
    2590  Miscellaneous
     D01360  Clenbuterol hydrochloride (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Clenbuterol
      D01360  Clenbuterol hydrochloride (JAN)
BRITE hierarchy
Other DBs
CAS: 
21898-19-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   X   Cl   29.9109  -18.3736
            2   C1d C    28.0218  -15.1576
            3   N1b N    26.7642  -15.8563
            4   C1a C    29.2794  -14.3891
            5   C1b C    25.5765  -15.1576
            6   C1c C    24.3888  -15.8563
            7   C8y C    23.2011  -15.1576
            8   O1a O    24.3888  -17.2536
            9   C8x C    23.2011  -13.7603
            10  C8x C    22.0133  -15.8563
            11  C8y C    22.0133  -13.0617
            12  C8y C    20.7558  -15.1576
            13  C8y C    20.7558  -13.7603
            14  X   Cl   22.0133  -11.6644
            15  X   Cl   19.5680  -15.8563
            16  N1a N    19.5680  -13.0617
            17  C1a C    28.7356  -16.3812
            18  C1a C    27.3251  -13.9634
BOND        17
            1     2   3 1
            2     2   4 1
            3     3   5 1
            4     5   6 1
            5     6   7 1
            6     6   8 1
            7     7   9 1
            8     7  10 2
            9     9  11 2
            10   10  12 1
            11   11  13 1
            12   11  14 1
            13   12  15 1
            14   12  13 2
            15   13  16 1
            16    2  17 1
            17    2  18 1

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